Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F10 | P00742 | 10/20 | 0.43 |
| ▸ | HPGD | P15428 | 6/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | F2 | P00734 | 7/20 | 0.37 |
| ▸ | PRSS1 | P07477 | 6/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | PIK3CA | P42336 | 2/20 | 0.35 |
| ▸ | MTOR | P42345 | 2/20 | 0.35 |
| ▸ | KDR | P35968 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6325885 | 0.78 | F10 (0.44) | F10HPGDLMNAF2PRSS1 | |
| SCHEMBL6329955 | 0.78 | F10 (0.43) | F10F2PRSS1 | |
| SCHEMBL6329483 | 0.78 | PDK2 (0.36) | F10F2PRSS1 | |
| SCHEMBL6322359 | 0.78 | F10 (0.45) | F10HPGDF2PRSS1 | |
| SCHEMBL6324691 | 0.77 | AURKA (0.48) | F10HPGDALDH1A1LMNASMN1; SMN2 | |
| SCHEMBL6323903 | 0.74 | LOXL2 (0.41) | F10HPGDF2PRSS1KDR | |
| SCHEMBL6322317 | 0.73 | NPC1 (0.36) | NPC1RAB9A | |
| SCHEMBL6323985 | 0.73 | CAMK1D (0.39) | F10PRSS1 | |
| SCHEMBL6326452 | 0.73 | TPSAB1 (0.39) | F10F2PRSS1NPC1RAB9A | |
| SCHEMBL6332625 | 0.70 | HPGD (0.52) | HPGDALDH1A1LMNATDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050107409-A1 | Aromatic bicyclic compounds, preparation thereof and their use as pharmaceutical compositions | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2005-05-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050107409-A1 | Aromatic bicyclic compounds, preparation thereof and their use as pharmaceutical compositions | F12, F2, F11 | F10 11/4885HPGD 1428/4885ALDH1A1 1078/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.