Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RHEB | Q15382 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.46 |
| ▸ | TTR | P02766 | 1/20 | 0.46 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | HTR1A | P08908 | 1/20 | 0.39 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.39 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.39 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | PNMT | P11086 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | ATM | Q13315 | 1/20 | 0.35 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6325195 | 0.82 | RHEB (0.60) | RHEBMEN1KMT2ANPSR1TTR | |
| SCHEMBL8515835 | 0.80 | MEN1 (0.53) | MEN1KMT2ANPSR1TTRHSP90AA1 | |
| SCHEMBL22069692 | 0.80 | RHEB (0.45) | RHEBMEN1KMT2ANPSR1TTR | |
| SCHEMBL11053300 | 0.79 | CYP3A4 (0.57) | RHEBMEN1KMT2ANPSR1TTR | |
| SCHEMBL28215828 | 0.79 | NR4A1 (0.53) | RHEBMEN1KMT2ANPSR1MAPT | |
| SCHEMBL28141123 | 0.74 | ALDH1A1 (0.40) | RHEBMEN1KMT2ANPSR1TTR | |
| SCHEMBL11453570 | 0.73 | TTR (0.58) | RHEBMEN1KMT2ATTRHSP90AA1 | |
| SCHEMBL11819263 | 0.73 | CYP1A2 (0.59) | MEN1KMT2ATTRMAPTALDH1A1 | |
| SCHEMBL22114111 | 0.73 | MAPT (0.46) | RHEBMEN1KMT2ANPSR1TTR | |
| SCHEMBL22069620 | 0.73 | SLC6A2 (0.45) | RHEBMEN1KMT2ANPSR1TTR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 40 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20130303781-A1 | PROCESS FOR PREPARATION OF TRICLABENDAZOLE | SEQUENT SCIENTIFIC LIMITED (IN) | 2013-11-14 | — | — | US | claimed |
| EP-2642995-A2 | PROCESS FOR PREPARATION OF TRICLABENDAZOLE | Sequent Scientific Ltd. (IN) | 2013-10-02 | — | — | EP | claimed |
| WO-2012070068-A2 | PROCESS FOR PREPARATION OF TRICLABENDAZOLE | SEQUENT SCIENTIFIC LIMITED (IN) | 2012-05-31 | — | — | WO | claimed |
| EP-3763706-A1 | PARASITICIDAL COMPOSITIONS COMPRISING BENZIMIDAZOLE DERIVATIVES, METHODS AND USES THEREOF | Boehringer Ingelheim Animal Health USA Inc. (US) | 2021-01-13 | — | — | EP | disclosed |
| EP-3453702-A2 | PARASITICIDAL COMPOSITIONS COMPRISING BENZIMIDAZOLE DERIVATIVES, METHODS AND USES THEREOF | Merial, Inc. (US) | 2019-03-13 | — | — | EP | disclosed |
| EP-2895465-B1 | PARASITICIDAL COMPOSITIONS COMPRISING BENZIMIDAZOLE DERIVATIVES, METHODS AND USES THEREOF | MERIAL INC (US) | 2018-10-03 | — | — | EP | disclosed |
| US-9695129-B2 | Parasiticidal compositions comprising benzimidazole derivatives, methods and uses thereof | MERIAL INC. (US) | 2017-07-04 | — | — | US | disclosed |
| US-9695129-B2 | Parasiticidal compositions comprising benzimidazole derivatives, methods and uses thereof | MERIAL INC. (US) | 2017-07-04 | — | — | US | disclosed |
| US-9695129-B2 | Parasiticidal compositions comprising benzimidazole derivatives, methods and uses thereof | MERIAL INC. (US) | 2017-07-04 | — | — | US | disclosed |
| CN-106632067-A | Method for preparing triclabendazole serving as medicine for animal distomiasis | 杭州洪桥生物技术有限公司 | 2017-05-10 | — | — | CN | disclosed |
| US-20160251317-A1 | PARASITICIDAL COMPOSITIONS COMPRISING BENZIMIDAZOLE DERIVATIVES, METHODS AND USES THEREOF | MERIAL INC (US) | 2016-09-01 | — | — | US | disclosed |
| EP-2642995-A2 | PROCESS FOR PREPARATION OF TRICLABENDAZOLE | Sequent Scientific Ltd. (IN) | 2013-10-02 | — | — | EP | disclosed |
| EP-2642995-A2 | PROCESS FOR PREPARATION OF TRICLABENDAZOLE | Sequent Scientific Ltd. (IN) | 2013-10-02 | — | — | EP | disclosed |
| WO-2012070068-A3 | PROCESS FOR PREPARATION OF TRICLABENDAZOLE | SEQUENT SCIENTIFIC LIMITED (IN) | 2012-07-19 | — | — | WO | disclosed |
| WO-2012070068-A2 | PROCESS FOR PREPARATION OF TRICLABENDAZOLE | SEQUENT SCIENTIFIC LIMITED (IN) | 2012-05-31 | — | — | WO | disclosed |
| WO-2012070068-A2 | PROCESS FOR PREPARATION OF TRICLABENDAZOLE | SEQUENT SCIENTIFIC LIMITED (IN) | 2012-05-31 | — | — | WO | disclosed |
| WO-2012070068-A2 | PROCESS FOR PREPARATION OF TRICLABENDAZOLE | SEQUENT SCIENTIFIC LIMITED (IN) | 2012-05-31 | — | — | WO | disclosed |
| US-5322853-A | For controlling or preventing an attack on plants by phytopathogenic microorganisms | CIBA-GEIGY CORPORATION (US) | 1994-06-21 | — | — | US | disclosed |
| EP-0462931-B1 | Benzotriazole-1-sulfonyl derivatives with microbicidal properties | CIBA GEIGY AG (CH) | 1994-04-13 | — | — | EP | disclosed |
| EP-0462931-A1 | Benzotriazole-1-sulfonyl derivatives with microbicidal properties | CIBA-GEIGY AG (CH) | 1991-12-27 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130303781-A1 | PROCESS FOR PREPARATION OF TRICLABENDAZOLE | NIT2, CA3, TET3 | RHEB 4307/4885MEN1 1675/4885KMT2A 455/4885 |
| US-20160251317-A1 | PARASITICIDAL COMPOSITIONS COMPRISING BENZIMIDAZOLE DERIVATIVES, METHODS AND USES THEREOF | LIPC, CYP3A43, CYP51A1 | RHEB 3425/4885MEN1 3898/4885KMT2A 3121/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.