Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN5 | P54829 | 1/20 | 0.58 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.53 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | MRGPRX4 | Q96LA9 | 3/20 | 0.47 |
| ▸ | MAPT | P10636 | 3/20 | 0.46 |
| ▸ | NR4A2 | P43354 | 2/20 | 0.45 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.44 |
| ▸ | NR4A3 | Q92570 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | HPGD | P15428 | 3/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.44 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.44 |
| ▸ | PRKX | P51817 | 1/20 | 0.44 |
| ▸ | ACVR1 | Q04771 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6320131 | 0.92 | TRPM8 (0.51) | PTPN5TRPM8POLBMAPTKDM4E | |
| SCHEMBL6319864 | 0.90 | PTPN5 (0.58) | PTPN5TRPM8POLBMRGPRX4NR4A2 | |
| SCHEMBL6322652 | 0.88 | POLB (0.61) | PTPN5POLBMAPTKDM4EALDH1A1 | |
| SCHEMBL5882137 | 0.86 | PTPN5 (0.74) | PTPN5TRPM8POLBMRGPRX4MAPT | |
| SCHEMBL6318392 | 0.84 | MCL1 (0.49) | PTPN5TRPM8 | |
| SCHEMBL5881790 | 0.82 | PTPN5 (0.58) | PTPN5POLBMAPTNR4A2KDM4E | |
| SCHEMBL6318627 | 0.82 | PTPN5 (0.50) | PTPN5TRPM8POLBMRGPRX4MAPT | |
| SCHEMBL5881662 | 0.82 | PTPN5 (0.53) | PTPN5POLBMAPTKDM4EALDH1A1 | |
| SCHEMBL6319268 | 0.81 | PTPN5 (0.52) | PTPN5POLBKDM4EALDH1A1HPGD | |
| SCHEMBL5881620 | 0.81 | PTPN5 (0.57) | PTPN5POLBMRGPRX4MAPTNR4A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050171185-A1 | Indole derivatives | FUJISAWA PHARMACEUTICAL CO., LTD., A JAPANESE CORPORATION | 2005-08-04 | — | — | US | disclosed |
| CN-1150167-C | Indole derivatives | ����ҩƷ��ҵ��ʽ���� | 2004-05-19 | — | — | CN | disclosed |
| CN-1303371-A | Indole derivatives | FUJISAWA PHARMACEUTICAL CO (JP) | 2001-07-11 | — | — | CN | disclosed |
| EP-1070705-A1 | INDOLE DERIVATIVES | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2001-01-24 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050171185-A1 | Indole derivatives | PDE5A, IGFBP5, HTR5A | PTPN5 108/4885TRPM8 3042/4885POLB 3673/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.