Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 11/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.55 |
| ▸ | KDM5A | P29375 | 2/20 | 0.50 |
| ▸ | KDM3A | Q9Y4C1 | 2/20 | 0.50 |
| ▸ | JMJD1C | Q15652 | 1/20 | 0.50 |
| ▸ | HPGD | P15428 | 2/20 | 0.49 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 3/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 2/20 | 0.45 |
| ▸ | ACMSD | Q8TDX5 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | KDM6B | O15054 | 1/20 | 0.42 |
| ▸ | TET3 | O43151 | 1/20 | 0.42 |
| ▸ | KDM4A | O75164 | 1/20 | 0.42 |
| ▸ | BBOX1 | O75936 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | KDM5C | P41229 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12609250 | 0.84 | ALDH1A1 (0.44) | KDM4EALDH1A1KDM5AKDM3AJMJD1C | |
| SCHEMBL6650242 | 0.82 | KDM4E (0.42) | KDM4EALDH1A1KDM5AKDM3AJMJD1C | |
| SCHEMBL29825918 | 0.80 | KDM4E (0.47) | KDM4EALDH1A1KDM5AKDM3AJMJD1C | |
| SCHEMBL1790483 | 0.79 | MAPK1 (0.43) | KDM4EALDH1A1KDM3AHPGDALOX15 | |
| SCHEMBL26555468 | 0.79 | HPGD (0.41) | KDM4EALDH1A1HPGDALOX15HSD17B10 | |
| SCHEMBL7214552 | 0.79 | TDP1 (0.51) | KDM4EALDH1A1KDM5AKDM3AJMJD1C | |
| SCHEMBL6981215 | 0.79 | HRH3 (0.45) | KDM4EALDH1A1KDM5AKDM3AJMJD1C | |
| SCHEMBL3560191 | 0.77 | KDM4E (0.55) | KDM4EALDH1A1KDM5AKDM3AJMJD1C | |
| SCHEMBL30740854 | 0.76 | JAK3 (0.50) | KDM4EALDH1A1KDM5AKDM3AJMJD1C | |
| SCHEMBL27955600 | 0.75 | CYP1A2 (0.57) | KDM4EALDH1A1HPGDHSD17B10KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 32 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116285775-A | High-performance chloroprene rubber adhesive and preparation method thereof | 上谷新材料(苏州)有限公司 | 2023-06-23 | — | — | CN | claimed |
| CN-116102700-A | Softening agent and preparation method thereof | 江苏奥斯佳材料科技股份有限公司 | 2023-05-12 | — | — | CN | claimed |
| CN-112961303-B | Softening agent for soft polyurethane foam and application thereof | 江苏奥斯佳材料科技股份有限公司 | 2023-01-03 | — | — | CN | claimed |
| CN-112961303-A | Softening agent for soft polyurethane foam and application thereof | 江苏奥斯佳材料科技股份有限公司 | 2021-06-15 | — | — | CN | claimed |
| CN-112940212-A | Polyurethane catalyst, automotive polyurethane material and preparation method thereof | 江苏奥斯佳材料科技股份有限公司 | 2021-06-11 | — | — | CN | claimed |
| CN-104558467-B | A kind of catalysts for polyurethanes and its application | 江苏奥斯佳材料科技有限公司 | 2018-02-23 | — | — | CN | claimed |
| CN-104558468-B | A kind of application of catalysts for polyurethanes in hard polyurethane material is synthesized | 江苏奥斯佳材料科技有限公司 | 2018-02-23 | — | — | CN | claimed |
| CN-104558469-B | A kind of application of catalysts for polyurethanes in flexible polyurethane foam is synthesized | 江苏奥斯佳材料科技有限公司 | 2018-02-23 | — | — | CN | claimed |
| CN-104558469-A | Application of polyurethane catalyst in synthesis of flexible polyurethane foamed plastic | JIANGSU AOSIJIA MATERIAL SCIENCE & TECHNOLOGY CO LTD | 2015-04-29 | — | — | CN | claimed |
| CN-104558467-A | Polyurethane catalyst and application thereof | JIANGSU AOSIJIA MATERIAL SCIENCE & TECHNOLOGY CO LTD | 2015-04-29 | — | — | CN | claimed |
| CN-104558468-A | Application of polyurethane catalyst in synthesis of rigid polyurethane material | JIANGSU AOSIJIA MATERIAL SCIENCE & TECHNOLOGY CO LTD | 2015-04-29 | — | — | CN | claimed |
| CN-117043154-A | GPCR receptor agonists, pharmaceutical compositions comprising same, and methods of use thereof | 卡莫特医疗有限公司 | 2023-11-10 | — | — | CN | disclosed |
| CN-116285775-A | High-performance chloroprene rubber adhesive and preparation method thereof | 上谷新材料(苏州)有限公司 | 2023-06-23 | — | — | CN | disclosed |
| CN-116120515-A | Flexible polyurethane foam and method for producing the same | 江苏奥斯佳材料科技股份有限公司 | 2023-05-16 | — | — | CN | disclosed |
| CN-116102700-A | Softening agent and preparation method thereof | 江苏奥斯佳材料科技股份有限公司 | 2023-05-12 | — | — | CN | disclosed |
| US-8507485-B2 | Cyclic compound having pyrimidinylalkylthio group | SANTEN PHARMACEUTICAL CO., LTD. (JP) | 2013-08-13 | — | — | US | disclosed |
| US-20110124646-A1 | Novel cyclic compound having pyrimidinylalkylthio group | SANTEN PHARMACEUTICAL CO., LTD. (JP) | 2011-05-26 | — | — | US | disclosed |
| CN-101080396-A | Quinoxalines as B Raf inhibitors | ASTRAZENECA AB (SE) | 2007-11-28 | — | — | CN | disclosed |
| US-6867210-B2 | Aryl substituted pyrimidines | EURO-CELTIQUE S.A. (LU) | 2005-03-15 | — | — | US | disclosed |
| US-20050043305-A1 | Aryl substituted pyridines, pyrimidines, pyrazines and triazines and the use thereof | EURO-CELTIQUE S.A. (LU) | 2005-02-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050043305-A1 | Aryl substituted pyridines, pyrimidines, pyrazines and triazines and the use thereof | CACNA1S, CACNA1C, KYNU | KDM4E 2686/4885ALDH1A1 226/4885KDM5A 793/4885 |
| US-20110124646-A1 | Novel cyclic compound having pyrimidinylalkylthio group | FLT1, VEGFA, FLT4 | KDM4E 3990/4885ALDH1A1 185/4885KDM5A 4083/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.