Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.48 |
| ▸ | MAPT | P10636 | 3/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | PIN1 | Q13526 | 5/20 | 0.40 |
| ▸ | MME | P08473 | 1/20 | 0.38 |
| ▸ | CTSL | P07711 | 1/20 | 0.36 |
| ▸ | LPAR1 | Q92633 | 2/20 | 0.35 |
| ▸ | LPAR3 | Q9UBY5 | 2/20 | 0.35 |
| ▸ | MMEL1 | Q495T6 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6331031 | 0.86 | PIN1 (0.56) | NPSR1MAPTALDH1A1MAPK1PIN1 | |
| SCHEMBL6271032 | 0.73 | GAA (0.43) | ALDH1A1MAPK1PIN1 | |
| SCHEMBL6276477 | 0.69 | PIN1 (0.46) | PIN1CTSL | |
| SCHEMBL6323808 | 0.69 | PIN1 (0.75) | PIN1 | |
| SCHEMBL6274827 | 0.66 | PIN1 (0.59) | ALDH1A1PIN1MMEMMEL1 | |
| SCHEMBL6325242 | 0.65 | PIN1 (0.76) | PIN1 | |
| SCHEMBL10379563 | 0.64 | GLA (0.46) | ALDH1A1 | |
| SCHEMBL4673037 | 0.64 | ALDH1A1 (0.68) | NPSR1MAPTALDH1A1MAPK1 | |
| SCHEMBL6323785 | 0.64 | PIN1 (0.77) | PIN1CTSLLPAR1LPAR3 | |
| SCHEMBL19509036 | 0.63 | ALDH1A1 (0.61) | MAPTALDH1A1MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050250742-A1 | Phosphate/sulfate ester compounds and pharmaceutical composition for inhibiting protein interacting NIMA (PIN1) | PFIZER INC. | 2005-11-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050250742-A1 | Phosphate/sulfate ester compounds and pharmaceutical composition for inhibiting protein interacting NIMA (PIN1) | PIN1, PSTPIP2, NIM1K | NPSR1 1587/4885MAPT 110/4885ALDH1A1 4852/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.