SCHEMBL6325404

SCHEMBL6325404

CCCCOS(=O)(=O)c1ccccc1N

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP2C9 P11712 2/20 0.50
CYP1A2 P05177 1/20 0.50
CYP2C19 P33261 1/20 0.50
ALDH1A1 P00352 3/20 0.46
HSD17B10 Q99714 2/20 0.46
GAA P10253 1/20 0.46
CA2 P00918 13/20 0.44
CA1 P00915 12/20 0.44
CA9 Q16790 10/20 0.44
CA12 O43570 5/20 0.44
CA7 P43166 5/20 0.44
CA14 Q9ULX7 4/20 0.44
CA4 P22748 3/20 0.44
CA6 P23280 3/20 0.44
CA5A P35218 3/20 0.44
CA5B Q9Y2D0 3/20 0.44
KDM4E B2RXH2 1/20 0.41
POLB P06746 1/20 0.41
HTR6 P50406 1/20 0.41
TSHR P16473 2/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31299789 0.94 ALDH1A1 (0.49) CYP2C9CYP1A2CYP2C19ALDH1A1HSD17B10
SCHEMBL9136812 0.94 ALDH1A1 (0.49) CYP2C9CYP1A2CYP2C19ALDH1A1HSD17B10
SCHEMBL27701264 0.90 GAA (0.48) CYP2C9CYP1A2CYP2C19ALDH1A1HSD17B10
SCHEMBL7190008 0.88 CA2 (0.47) CYP2C9CYP1A2CYP2C19ALDH1A1CA2
SCHEMBL29415366 0.88 CA2 (0.47) CYP2C9CYP1A2CYP2C19ALDH1A1CA2
SCHEMBL8779870 0.84 GAA (0.54) CYP2C9CYP1A2CYP2C19ALDH1A1HSD17B10
SCHEMBL27950977 0.82 GAA (0.52) CYP2C9CYP1A2CYP2C19ALDH1A1HSD17B10
SCHEMBL16047004 0.82 CA1 (0.48) ALDH1A1CA2CA1CA9CA12
SCHEMBL27937639 0.82 GAA (0.52) CYP2C9CYP1A2CYP2C19ALDH1A1HSD17B10
SCHEMBL27465812 0.81 CTSB (0.42) CYP2C9CYP1A2CYP2C19ALDH1A1CA2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6858565-B2 Thermosensitive recording material and novel color developer compounds OJI PAPER CO., LTD. (JP) 2005-02-22 US disclosed
US-20030040434-A1 Thermosensitive recording material and novel color developer compounds OJI PAPER CO., LTD. (JP) 2003-02-27 US disclosed
EP-1264707-A2 Thermosensitive recording material and novel color developer compounds OJI PAPER CO., LTD. (JP) 2002-12-11 EP disclosed