Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 9/20 | 0.97 |
| ▸ | MITF | O75030 | 5/20 | 0.97 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.97 |
| ▸ | HTT | P42858 | 3/20 | 0.97 |
| ▸ | RAB9A | P51151 | 2/20 | 0.97 |
| ▸ | ATM | Q13315 | 2/20 | 0.97 |
| ▸ | PAX8 | Q06710 | 2/20 | 0.97 |
| ▸ | GFER | P55789 | 1/20 | 0.97 |
| ▸ | NTSR1 | P30989 | 2/20 | 0.77 |
| ▸ | LMNA | P02545 | 9/20 | 0.75 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.75 |
| ▸ | MAPT | P10636 | 5/20 | 0.67 |
| ▸ | NLRP1 | Q9C000 | 1/20 | 0.67 |
| ▸ | TP53 | P04637 | 4/20 | 0.61 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.61 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.61 |
| ▸ | JAK2 | O60674 | 2/20 | 0.55 |
| ▸ | MEN1 | O00255 | 1/20 | 0.54 |
| ▸ | THRB | P10828 | 1/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6321267 | 0.98 | SMN1; SMN2 (0.94) | SMN1; SMN2MITFALDH1A1HTTRAB9A | |
| SCHEMBL10852952 | 0.89 | SMN1; SMN2 (0.77) | SMN1; SMN2MITFALDH1A1HTTRAB9A | |
| SCHEMBL23094153 | 0.86 | SMN1; SMN2 (1.00) | SMN1; SMN2MITFALDH1A1HTTRAB9A | |
| Hydrochloric Acid SCHEMBL9850640 | 0.86 | SMN1; SMN2 (0.78) | SMN1; SMN2MITFALDH1A1HTTRAB9A | |
| SCHEMBL6320116 | 0.86 | SMN1; SMN2 (0.81) | SMN1; SMN2MITFALDH1A1HTTRAB9A | |
| Hydrochloric Acid SCHEMBL9850694 | 0.85 | SMN1; SMN2 (0.76) | SMN1; SMN2MITFALDH1A1HTTRAB9A | |
| SCHEMBL10851628 | 0.85 | SMN1; SMN2 (0.97) | SMN1; SMN2MITFALDH1A1HTTRAB9A | |
| SCHEMBL7592795 | 0.85 | MITF (0.71) | SMN1; SMN2MITFALDH1A1HTTRAB9A | |
| SCHEMBL12282101 | 0.85 | MITF (0.71) | SMN1; SMN2MITFALDH1A1HTTRAB9A | |
| Hydrochloric Acid SCHEMBL10851947 | 0.84 | LMNA (0.95) | SMN1; SMN2MITFALDH1A1HTTRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050272036-A1 | Ketones | ASTRAZENECA AB (SE) | 2005-12-08 | — | — | US | disclosed |