Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A4 | P31645 | 1/20 | 0.54 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | LDHA | P00338 | 1/20 | 0.41 |
| ▸ | AOC3 | Q16853 | 2/20 | 0.39 |
| ▸ | TAAR1 | Q96RJ0 | 3/20 | 0.38 |
| ▸ | IDO1 | P14902 | 2/20 | 0.38 |
| ▸ | AGXT | P21549 | 2/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL636098 | 0.84 | SLC6A4 (0.51) | SLC6A4CYP1A2CYP2D6CYP2C19LDHA | |
| SCHEMBL637388 | 0.80 | SLC6A4 (0.50) | SLC6A4CYP1A2CYP2D6CYP2C19AOC3 | |
| SCHEMBL635989 | 0.79 | SLC6A4 (0.56) | SLC6A4CYP1A2CYP2D6CYP2C19AOC3 | |
| SCHEMBL6327948 | 0.79 | SLC6A4 (0.57) | SLC6A4CYP1A2CYP2D6CYP2C19LDHA | |
| SCHEMBL3946088 | 0.76 | SLC6A4 (0.53) | SLC6A4CYP1A2CYP2D6CYP2C19AOC3 | |
| SCHEMBL636064 | 0.76 | SLC6A4 (0.53) | SLC6A4CYP1A2CYP2D6CYP2C19AOC3 | |
| SCHEMBL21175654 | 0.74 | SLC6A4 (0.63) | SLC6A4CYP1A2CYP2D6CYP2C19LDHA | |
| SCHEMBL9584268 | 0.73 | SLC6A4 (0.58) | SLC6A4CYP1A2CYP2D6CYP2C19LDHA | |
| SCHEMBL14032256 | 0.73 | SLC6A4 (0.61) | SLC6A4CYP1A2CYP2D6CYP2C19LDHA | |
| Para-Methoxyamphetamine SCHEMBL264634 | 0.71 | SLC6A4 (1.00) | SLC6A4CYP1A2CYP2D6CYP2C19TAAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2814813-B1 | PROCESS FOR THE STEREOSELECTIVE PREPARATION OF A PYRAZOLE CARBOXAMIDE | SYNGENTA PARTICIPATIONS AG (CH) | 2016-02-10 | — | — | EP | disclosed |
| US-9120759-B2 | Process for the stereoselective preparation of a pyrazole carboxamide | SYNGENTA PARTICIPATIONS AG (CH) | 2015-09-01 | — | — | US | disclosed |
| US-20140364622-A1 | PROCESS FOR THE STEREOSELECTIVE PREPARATION OF A PYRAZOLE CARBOXAMIDE | SYNGENTA PARTICIPATIONS AG (CH) | 2014-12-11 | — | — | US | disclosed |
| US-20050272930-A1 | Process for the prepation of 3-hydroxy-(2-thienyl)propanamines | HEMS WILLIAM | 2005-12-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140364622-A1 | PROCESS FOR THE STEREOSELECTIVE PREPARATION OF A PYRAZOLE CARBOXAMIDE | CYP4B1, CYP3A4, CYP2E1 | SLC6A4 2724/4885CYP1A2 9/4885CYP2D6 18/4885 |
| US-20050272930-A1 | Process for the prepation of 3-hydroxy-(2-thienyl)propanamines | PNMT, HPD, HRH3 | SLC6A4 846/4885CYP1A2 83/4885CYP2D6 117/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.