Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 2/20 | 0.67 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.67 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.54 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.54 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.54 |
| ▸ | BRD4 | O60885 | 1/20 | 0.53 |
| ▸ | BRPF1 | P55201 | 1/20 | 0.53 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.51 |
| ▸ | NPC1 | O15118 | 3/20 | 0.51 |
| ▸ | RAB9A | P51151 | 3/20 | 0.51 |
| ▸ | XBP1 | P17861 | 1/20 | 0.51 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | ATM | Q13315 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Pyrrole SCHEMBL9110324 | 0.90 | CYP1A2 (0.54) | CYP1A2CYP3A4NPSR1ALDH1A1MAPK1 | |
| SCHEMBL28146850 | 0.89 | NPSR1 (0.56) | CYP1A2CYP3A4NPSR1ALDH1A1MAPK1 | |
| SCHEMBL13983006 | 0.86 | ALDH1A1 (0.63) | CYP1A2CYP3A4NPSR1ALDH1A1MAPK1 | |
| SCHEMBL14236103 | 0.85 | NPSR1 (0.70) | CYP1A2CYP3A4NPSR1ALDH1A1MAPK1 | |
| SCHEMBL1627629 | 0.82 | HPGD (0.76) | CYP1A2ALDH1A1MAPK1L3MBTL1SMN1; SMN2 | |
| SCHEMBL6321766 | 0.82 | CYP1A2 (0.58) | CYP1A2CYP3A4NPSR1ALDH1A1MAPK1 | |
| SCHEMBL8352639 | 0.81 | CYP1A2 (1.00) | CYP1A2CYP3A4NPSR1ALDH1A1MAPK1 | |
| SCHEMBL13919303 | 0.81 | IGF1R (0.61) | CYP1A2CYP3A4NPSR1ALDH1A1MAPK1 | |
| SCHEMBL7258145 | 0.79 | HPGD (0.76) | CYP1A2ALDH1A1MAPK1L3MBTL1SMN1; SMN2 | |
| SCHEMBL1450411 | 0.77 | HPGD (0.80) | CYP1A2CYP3A4NPSR1ALDH1A1MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0527186-A4 | — | UNIV ILLINOIS (US) | 1995-01-18 | — | — | EP | claimed |
| EP-0527186-A1 | PHOTODYNAMIC PLANT DEFOLIANTS AND CHLOROPHYLL BIOSYNTHESIS MODULATORS | The Board of Trustees for the University of Illinois (US) | 1993-02-17 | — | — | EP | claimed |
| WO-1991016820-A1 | PHOTODYNAMIC PLANT DEFOLIANTS AND CHLOROPHYLL BIOSYNTHESIS MODULATORS | THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS (US) | 1991-11-14 | — | — | WO | claimed |
| US-6878786-B2 | Process for the polymerization of olefins | BASELL POLYOLEFINE GMBH (DE) | 2005-04-12 | — | — | US | disclosed |
| US-6841501-B2 | Catalyst system for the polymerization of olefins | BASELL POLIOLEFINE ITALIA S.P.A. (IT) | 2005-01-11 | — | — | US | disclosed |
| EP-1173445-B1 | ORGANOMETALLIC COMPOUND USEFUL AS COCATALYST FOR POLYMERIZING OLEFINS | BASELL POLYOLEFINE GMBH (DE) | 2004-06-09 | — | — | EP | disclosed |
| US-20040030153-A1 | Process for the polymerization of olefins | EQUISTAR CHEMICALS, LP | 2004-02-12 | — | — | US | disclosed |
| US-20030228976-A1 | Catalyst system for the polymerization of olefins | RESCONI LUIGI (IT) | 2003-12-11 | — | — | US | disclosed |
| US-6608224-B2 | Useful as cocatalysts for polymerizing olefins | BASELL POLYOLEFINE GMBH (DE) | 2003-08-19 | — | — | US | disclosed |
| US-20020038036-A1 | \"Catalyst system for the polymerization of olefins\ | EQUISTAR CHEMICALS, LP | 2002-03-28 | — | — | US | disclosed |
| EP-1173445-A1 | ORGANOMETALLIC COMPOUND USEFUL AS COCATALYST FOR POLYMERIZING OLEFINS | Basell Technology Company B.V. (NL) | 2002-01-23 | — | — | EP | disclosed |
| WO-2001062764-A1 | ORGANOMETALLIC COMPOUND USEFUL AS COCATALYST FOR POLYMERIZING OLEFINS | BASELL TECHNOLOGY COMPANY B.V. (NL) | 2001-08-30 | — | — | WO | disclosed |
| US-5242892-A | With 5-aminolevulinic acid | THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS (US) | 1993-09-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040030153-A1 | Process for the polymerization of olefins | MT-CO1, UQCRC1, MT-CO3 | CYP1A2 523/4885CYP3A4 824/4885NPSR1 4137/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.