⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6318706 | 0.81 | ABL1 (0.30) | — | |
| SCHEMBL6323031 | 0.77 | SLC22A3 (0.40) | — | |
| SCHEMBL6272028 | 0.72 | ALPL (0.37) | — | |
| SCHEMBL6318605 | 0.69 | NOTUM (0.33) | — | |
| SCHEMBL6319816 | 0.69 | PDE5A (0.32) | — | |
| SCHEMBL6319568 | 0.69 | SLC22A3 (0.40) | — | |
| SCHEMBL6320054 | 0.68 | NOTUM (0.31) | — | |
| SCHEMBL6318053 | 0.67 | NFKB1 (0.38) | — | |
| SCHEMBL6324258 | 0.66 | NOTUM (0.33) | — | |
| SCHEMBL6319387 | 0.65 | MEN1 (0.39) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050143349-A1 | Phosphorus containing compounds useful for the regulation of LDL and Lp(a) levels | QUATRX PHARMACEUTICALS CO. | 2005-06-30 | — | — | US | claimed |
| US-20050143349-A1 | Phosphorus containing compounds useful for the regulation of LDL and Lp(a) levels | QUATRX PHARMACEUTICALS CO. | 2005-06-30 | — | — | US | disclosed |