Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | HTT | P42858 | 3/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.36 |
| ▸ | RET | P07949 | 8/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | F2 | P00734 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6326173 | 0.85 | POLB (0.35) | POLBMAPTHTTSMN1; SMN2CYP1A2 | |
| SCHEMBL23982521 | 0.83 | RET (0.33) | RETGPR119 | |
| SCHEMBL20540301 | 0.79 | MAPT (0.45) | POLBMAPTHTTSMN1; SMN2CYP1A2 | |
| SCHEMBL26113587 | 0.79 | TRPA1 (0.32) | RET | |
| SCHEMBL26113583 | 0.79 | TRPA1 (0.32) | RET | |
| SCHEMBL31344227 | 0.78 | HTT (0.35) | POLBMAPTHTTSMN1; SMN2CYP1A2 | |
| SCHEMBL30640456 | 0.75 | KDM4E (0.42) | POLBHTTSMN1; SMN2RETALDH1A1 | |
| SCHEMBL26113923 | 0.74 | TRPA1 (0.30) | — | |
| SCHEMBL26113927 | 0.74 | TRPA1 (0.30) | — | |
| SCHEMBL4735920 | 0.72 | CYP3A4 (0.41) | MAPTSMN1; SMN2CYP1A2CYP2C19KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10351533-B2 | Process for the preparation of carbamoylamino pyrazole derivatives | SANDOZ AG (CH) | 2019-07-16 | — | — | US | disclosed |
| EP-3313821-B1 | PROCESS FOR THE PREPARATION OF CARBAMOYLAMINO PYRAZOLE DERIVATIVES | SANDOZ AG (CH) | 2019-04-10 | — | — | EP | disclosed |
| US-6924284-B2 | PARP inhibitors | ICOS CORPORATION (US) | 2005-08-02 | — | — | US | disclosed |
| US-20040087588-A1 | Parp inhibitors | ICOS CORPORATION | 2004-05-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040087588-A1 | Parp inhibitors | PARP1, PARP2, PARP11 | POLB 54/4885MAPT 729/4885HTT 1266/4885 |
| US-10351533-B2 | Process for the preparation of carbamoylamino pyrazole derivatives | PAICS, PPOX, DDC | POLB 577/4885MAPT 3863/4885HTT 3821/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.