SCHEMBL6326223

SCHEMBL6326223

COc1cc(CN(CCC(=O)NOC(C)(C)C)C(=O)C(C)C)ccc1OCc1ccccc1

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TRPM8 Q7Z2W7 1/20 0.56
MEN1 O00255 3/20 0.50
KMT2A Q03164 3/20 0.50
RAF1 P04049 6/20 0.49
MAP2K1 Q02750 6/20 0.49
APP P05067 1/20 0.49
MTNR1A P48039 2/20 0.48
MTNR1B P49286 2/20 0.48
KDM4E B2RXH2 2/20 0.47
CYP1A2 P05177 1/20 0.47
CYP3A4 P08684 1/20 0.47
CYP2D6 P10635 1/20 0.47
CYP2C9 P11712 1/20 0.47
BLM P54132 1/20 0.47
NPC1 O15118 1/20 0.44
PKM P14618 1/20 0.44
RAB9A P51151 1/20 0.44
HDAC1 Q13547 1/20 0.44
HDAC2 Q92769 1/20 0.44
ALDH1A1 P00352 2/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6327033 0.85 TRPM8 (0.72) TRPM8MEN1KMT2ARAF1MAP2K1
SCHEMBL6323367 0.79 BCHE (0.61) KMT2AAPPMTNR1AMTNR1BKDM4E
SCHEMBL6327346 0.75 TRPM8 (0.51) TRPM8MEN1KMT2ARAF1MAP2K1
SCHEMBL14463837 0.74 TRPM8 (0.72) TRPM8MEN1KMT2ARAF1MAP2K1
SCHEMBL14464537 0.74 TRPM8 (0.84) TRPM8MEN1KMT2ARAF1MAP2K1
SCHEMBL6322783 0.74 TRPM8 (0.52) TRPM8MEN1KMT2ARAF1MAP2K1
SCHEMBL6322780 0.74 TRPM8 (0.49) TRPM8MEN1KMT2ARAF1MAP2K1
SCHEMBL6324719 0.74 TRPM8 (0.49) TRPM8MEN1KMT2ARAF1MAP2K1
SCHEMBL6648580 0.73 TRPM8 (0.49) TRPM8MEN1KMT2ARAF1MAP2K1
SCHEMBL6327342 0.73 TRPM8 (0.49) TRPM8MEN1KMT2ARAF1MAP2K1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250230306-A1 POLYETHYLENE OR POLYPROPYLENE ARTICLES BASF SE (DE) 2025-07-17 US disclosed
EP-4308638-A1 USE OF A STABILIZER COMPOSITION FOR STABILIZING POLYOLEFIN RECYCLATES, STABILIZER COMPOSITION, MASTER BATCH CONCENTRATE, PLASTIC COMPOSITION, MOLDING COMPOUND OR MOLDING, METHOD FOR STABILIZING A POLYOLEFIN RECYCLATE AND USE OF A PLASTIC COMPOSITION Fraunhofer-Gesellschaft zur Förderung der angewandten Forschung e.V. (DE) 2024-01-24 EP disclosed
EP-4301810-A1 USE OF A STABILIZER COMPOSITION FOR STABILIZING ORGANIC MATERIALS, STABILIZER COMPOSITION, MASTER BATCH, COMPOSITION, MOLDING COMPOUND FOR MOLDINGS, PROCESS FOR OXIDATIVE, THERMAL AND ACTINIC STABILIZATION OF A THERMOPLASTIC, AND USE OF A COMPOSITION Fraunhofer-Gesellschaft zur Förderung der angewandten Forschung e.V. (DE) 2024-01-10 EP disclosed
WO-2022194672-A1 USE OF A STABILIZER COMPOSITION FOR STABILIZING POLYOLEFIN RECYCLATES, STABILIZER COMPOSITION, MASTER BATCH CONCENTRATE, PLASTIC COMPOSITION, MOLDING COMPOUND OR MOLDING, METHOD FOR STABILIZING A POLYOLEFIN RECYCLATE AND USE OF A PLASTIC COMPOSITION Fraunhofer-Gesellschaft zur Förderung der angewandten Forschung e.V. (DE) 2022-09-22 WO disclosed
WO-2022184687-A1 USE OF A STABILIZER COMPOSITION FOR STABILIZING ORGANIC MATERIALS, STABILIZER COMPOSITION, MASTER BATCH, COMPOSITION, MOLDING COMPOUND FOR MOLDINGS, PROCESS FOR OXIDATIVE, THERMAL AND ACTINIC STABILIZATION OF A THERMOPLASTIC, AND USE OF A COMPOSITION Fraunhofer-Gesellschaft zur Förderung der angewandten Forschung e.V. (DE) 2022-09-09 WO disclosed
US-20140107350-A1 Process for Preparing Episulfide Compounds ASAHI KASEI CHEMICALS CORPORATION (JP) 2014-04-17 US disclosed
US-20050228017-A1 Novel anticancer compounds MORPHOCHEM AKTIENGESELLSCHAFT FUR KOMBINATORISCHE CHEMIE 2005-10-13 US disclosed
US-20050176596-A1 Alkylaminosiloxanes as corrosion inhibitors CIBA SPECIALTY CHEMICAL CORP. 2005-08-11 US disclosed
US-6908956-B2 Stabilizer composition BASF AKTIENGESELLSCHAFT (DE) 2005-06-21 US disclosed
US-20050049336-A1 Stabilizer mixtures GUGUMUS FRANCOIS (CH) 2005-03-03 US disclosed
US-20040241111-A1 Highly compatible hydroxyphenyltriazine uv-absorbers CIBA SPECIALTY CHEMICALS CORP. 2004-12-02 US disclosed
EP-1442018-A1 NOVEL ANTICANCER COMPOUNDS Morphochem Aktiengesellschaft Für Kombinatorische Chemie (DE) 2004-08-04 EP disclosed
US-20040058604-A1 Antistatic flexible intermediate bulk container CIBA SPECIALTY CHEMICALS CORP. 2004-03-25 US disclosed
US-20030191213-A1 Novel flame retarding compounds CIBA SPECIALTY CHEMICALS CORP. 2003-10-09 US disclosed
WO-2003037865-A1 NOVEL ANTICANCER COMPOUNDS Morphochem Aktiengesellschaft für kombinatorische Chemie (DE) 2003-05-08 WO disclosed
US-20030060544-A1 Stabilizer composition BASF AKTIENGESELLSCHAFT (DE) 2003-03-27 US disclosed
US-20010009939-A1 STABILIZERS FOR POWDER COATINGS CIBA SPECIALTY CHEMICALS CORP. 2001-07-26 US disclosed
US-6265473-B1 STABILIZER; HEAT AND OXIDATION RESISTANCE; PHOTOSTABILITY CIBA SPECIALTY CHEMICALS CORP. 2001-07-24 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20050228017-A1 Novel anticancer compounds TP53, ABCG2, MCL1 TRPM8 2570/4885MEN1 1347/4885KMT2A 3367/4885
US-20040241111-A1 Highly compatible hydroxyphenyltriazine uv-absorbers TYR, HAAO, HTT TRPM8 714/4885MEN1 2757/4885KMT2A 2347/4885
US-20140107350-A1 Process for Preparing Episulfide Compounds TST, EPHX2, STS TRPM8 4287/4885MEN1 3754/4885KMT2A 867/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.