Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPM8 | Q7Z2W7 | 2/20 | 0.49 |
| ▸ | RAF1 | P04049 | 6/20 | 0.45 |
| ▸ | MAP2K1 | Q02750 | 6/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | BLM | P54132 | 1/20 | 0.44 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.43 |
| ▸ | APP | P05067 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.40 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6324719 | 0.83 | TRPM8 (0.49) | TRPM8RAF1MAP2K1MEN1KMT2A | |
| SCHEMBL6327342 | 0.82 | TRPM8 (0.49) | TRPM8RAF1MAP2K1MEN1KMT2A | |
| SCHEMBL6327033 | 0.79 | TRPM8 (0.72) | TRPM8RAF1MAP2K1MEN1KMT2A | |
| SCHEMBL6327346 | 0.78 | TRPM8 (0.51) | TRPM8RAF1MAP2K1MEN1KMT2A | |
| SCHEMBL6322783 | 0.77 | TRPM8 (0.52) | TRPM8RAF1MAP2K1MEN1KMT2A | |
| SCHEMBL6322780 | 0.75 | TRPM8 (0.49) | TRPM8RAF1MAP2K1MEN1KMT2A | |
| SCHEMBL6324716 | 0.75 | TRPM8 (0.47) | TRPM8RAF1MAP2K1MEN1KMT2A | |
| SCHEMBL6326223 | 0.73 | TRPM8 (0.56) | TRPM8RAF1MAP2K1MEN1KMT2A | |
| SCHEMBL14078310 | 0.72 | TRPM8 (0.62) | TRPM8RAF1MAP2K1MEN1KMT2A | |
| SCHEMBL9416658 | 0.70 | MEN1 (0.61) | TRPM8RAF1MAP2K1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1442018-A1 | NOVEL ANTICANCER COMPOUNDS | Morphochem Aktiengesellschaft Für Kombinatorische Chemie (DE) | 2004-08-04 | — | — | EP | disclosed |
| WO-2003037865-A1 | NOVEL ANTICANCER COMPOUNDS | Morphochem Aktiengesellschaft für kombinatorische Chemie (DE) | 2003-05-08 | — | — | WO | disclosed |