SCHEMBL632638

SCHEMBL632638

CS(=O)(=O)NCCNc1ccccc1

nearest known ligand 0.55

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
POLB P06746 2/20 0.55
KEAP1 Q14145 1/20 0.52
MAPT P10636 4/20 0.50
ALDH1A1 P00352 2/20 0.50
MEN1 O00255 2/20 0.46
KMT2A Q03164 2/20 0.46
CA12 O43570 1/20 0.46
CA2 P00918 1/20 0.46
CA9 Q16790 1/20 0.46
KDM4D Q6B0I6 1/20 0.45
NQO2 P16083 1/20 0.45
HTT P42858 2/20 0.44
L3MBTL1 Q9Y468 1/20 0.44
GAA P10253 1/20 0.41
NR3C2 P08235 1/20 0.41
SMN1; SMN2 Q16637 1/20 0.41
PKM P14618 1/20 0.41
NR3C1 P04150 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Sulfuric Acid SCHEMBL8070176 0.94 POLB (0.50) POLBKEAP1MAPTALDH1A1MEN1
Sulfuric Acid SCHEMBL8822471 0.93 POLB (0.49) POLBKEAP1MAPTALDH1A1MEN1
Sulfuric Acid SCHEMBL8645602 0.93 POLB (0.49) POLBKEAP1MAPTALDH1A1MEN1
SCHEMBL12311240 0.89 ALDH1A1 (0.63) POLBKEAP1MAPTALDH1A1MEN1
SCHEMBL2447012 0.81 MAPT (0.44) POLBMAPTMEN1KMT2ACA12
SCHEMBL10620019 0.81 ALDH1A1 (0.46) POLBMAPTALDH1A1MEN1KMT2A
SCHEMBL11448713 0.80 MAPT (0.70) MAPTALDH1A1KMT2AKDM4DHTT
SCHEMBL24594164 0.79 ALDH1A1 (0.46) POLBMAPTALDH1A1MEN1KMT2A
Hydrochloric Acid SCHEMBL11418488 0.79 MAPT (0.68) MAPTALDH1A1KMT2AKDM4DHTT
SCHEMBL9522970 0.79 CYP1A2 (0.45) POLBMAPTALDH1A1MEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 75 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-1096797-A They carry out painted method dyeing composition for keratinous fibres and application OREAL (FR) 1994-12-28 CN claimed
WO-2022191865-A1 HAIR COLORANT ASSESSMENT, SELECTION AND FORMULATION SYSTEM Innovative Beauty LLC (US) 2022-09-15 WO disclosed
US-20220283032-A1 Hair Colorant Assessment, Selection And Formulation System Innovative Beauty LLC (US) 2022-09-08 US disclosed
US-11378457-B1 Hair colorant assessment, selection and formulation system Innovative Beauty LLC (US) 2022-07-05 US disclosed
US-8586617-B2 Aminomethyl-4-imidazoles HOFFMANN-LA ROCHE INC. (US) 2013-11-19 US disclosed
EP-2076497-B1 AMINOMETHYL-4-IMIDAZOLES HOFFMANN LA ROCHE (CH) 2012-02-22 EP disclosed
US-7732124-B2 Silver halide color photographic light-sensitive material and color image-forming method FUJIFILM CORPORATION (JP) 2010-06-08 US disclosed
EP-2076497-A1 AMINOMETHYL-4-IMIDAZOLES F. Hoffmann-Roche AG (CH) 2009-07-08 EP disclosed
US-7556918-B2 Color photographic films comprising support having color developable light sensitive silver halide emulsion layers and color dye-forming couplers, used for high speed print reproduction; storage stability FUJIFILM CORPORATION (JP) 2009-07-07 US disclosed
US-20090130613-A1 Silver Halide color photographic light-sensitive material and color image-forming method DEGUCHI YASUAKI 2009-05-21 US disclosed
EP-0167173-B1 COLOR PHOTOGRAPHIC MATERIALS FUJI PHOTO FILM CO., LTD. (JP) 1987-12-23 EP disclosed
US-4695533-A PYRAZOLOTRIAZOLE MAGENTA COUPLER WITH SULFONE GROUP KONISHIROKU PHOTO INDUSTRY CO., LTD. (JP) 1987-09-22 US disclosed
US-4546068-A AROMATIC AMINE DEVELOPER, MANANESE AND OR CERIUM SALT, DIPHOSPHONIC ACID SEQUESTERING AGENT KONISHIROKU PHOTO INDUSTRY CO., LTD. (JP) 1985-10-08 US disclosed
US-4537856-A WATER SOLUBLE CHELATE COMPOUND AS STABILIZER KONISHIROKU PHOTO INDUSTRY CO., LTD. (JP) 1985-08-27 US disclosed
US-4473374-A Nitrated coupler compounds useful in direct dyeing and simultaneous oxidation and direct dyeing of keratinic fibers SOCIETE ANONYME DITE: L'OREAL (FR) 1984-09-25 US disclosed
US-4330291-A Nitrated coupler compounds useful in direct dyeing and simultaneous oxidation and direct dyeing of keratinic fibers SOCIETE ANONYME DITE: L'OREAL (FR) 1982-05-18 US disclosed
US-4301223-A ADDITION OF A METAL COMPLEX FUJI PHOTO FILM CO., LTD. (JP) 1981-11-17 US disclosed
US-4279990-A SILANOL AND SILANEDIOL COMPOUNDS TO PREVENT DISCOLORATION FUJI PHOTO FILM CO., LTD. (JP) 1981-07-21 US disclosed
US-3990896-A YELLOW COLOR FORMING COUPLERS WITH 5-ALKYLIDINE-3-HYDANTOINYL GROUPS FUJI PHOTO FILM CO., LTD. (JA) 1976-11-09 US disclosed
US-3948663-A Multi-layer color photographic light-sensitive material FUJI PHOTO FILM CO., LTD. (JA) 1976-04-06 US disclosed