Known targets — ChEMBL curated mechanism
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
The experimentally established mechanism targets of Sulfuric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 3/20 | 0.50 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.47 |
| ▸ | KDM4D | Q6B0I6 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 5/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | CA12 | O43570 | 1/20 | 0.42 |
| ▸ | CA2 | P00918 | 1/20 | 0.42 |
| ▸ | CA9 | Q16790 | 1/20 | 0.42 |
| ▸ | NQO2 | P16083 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 2/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | BLM | P54132 | 1/20 | 0.40 |
| ▸ | GFER | P55789 | 1/20 | 0.40 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Sulfuric Acid SCHEMBL8822471 | 0.98 | POLB (0.49) | POLBKEAP1KDM4DMAPTALDH1A1 | |
| Sulfuric Acid SCHEMBL8645602 | 0.98 | POLB (0.49) | POLBKEAP1KDM4DMAPTALDH1A1 | |
| SCHEMBL632638 | 0.94 | POLB (0.55) | POLBKEAP1KDM4DMAPTALDH1A1 | |
| SCHEMBL12311240 | 0.84 | ALDH1A1 (0.63) | POLBKEAP1MAPTALDH1A1MEN1 | |
| Sulfuric Acid SCHEMBL10826973 | 0.83 | CYP2D6 (0.41) | KDM4DMAPTALDH1A1MEN1KMT2A | |
| Methane SCHEMBL11118664 | 0.81 | ALDH1A1 (0.48) | MAPTALDH1A1MEN1KMT2ACA12 | |
| SCHEMBL10620019 | 0.80 | ALDH1A1 (0.46) | POLBKDM4DMAPTALDH1A1MEN1 | |
| SCHEMBL9522970 | 0.78 | CYP1A2 (0.45) | POLBKDM4DMAPTALDH1A1MEN1 | |
| Sulfuric Acid SCHEMBL11088015 | 0.77 | MTNR1A (0.55) | MAPTALDH1A1CA12CA9L3MBTL1 | |
| Sulfuric Acid SCHEMBL2484445 | 0.77 | ALDH1A1 (0.52) | POLBMAPTALDH1A1CA12CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1014187-A1 | Silver halide photographic element containing improved yellow dye-forming coupler | EASTMAN KODAK COMPANY (US) | 2000-06-28 | — | — | EP | disclosed |
| EP-0304001-A2 | Coupler for photographic use | KONICA CORPORATION (JP) | 1989-02-22 | — | — | EP | disclosed |
| US-4001020-A | DEVELOPING A SILVER HA1IDE EMULSION IN CONTACT WITH A HETEROCYCLIC THIONE AND A POLYALKYLENE OXIDE | FUJI PHOTO FILM CO., LTD. (JA) | 1977-01-04 | — | — | US | disclosed |