Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.44 |
| ▸ | HTT | P42858 | 2/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | HSD17B2 | P37059 | 4/20 | 0.43 |
| ▸ | HSD17B1 | P14061 | 2/20 | 0.43 |
| ▸ | KDM4D | Q6B0I6 | 1/20 | 0.43 |
| ▸ | HTR7 | P34969 | 2/20 | 0.42 |
| ▸ | UQCRB | P14927 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.39 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.39 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11508113 | 0.82 | CYP3A4 (0.56) | CYP1A2ALDH1A1CYP3A4HTTCYP2D6 | |
| SCHEMBL11448713 | 0.82 | MAPT (0.70) | CYP1A2ALDH1A1CYP3A4HTTCYP2D6 | |
| Hydrochloric Acid SCHEMBL11418488 | 0.81 | MAPT (0.68) | CYP1A2ALDH1A1CYP3A4HTTCYP2D6 | |
| SCHEMBL10620019 | 0.80 | ALDH1A1 (0.46) | ALDH1A1CYP3A4MAPTKDM4DTSHR | |
| SCHEMBL632638 | 0.79 | POLB (0.55) | ALDH1A1HTTMAPTKDM4DGAA | |
| SCHEMBL14065536 | 0.78 | HRH3 (0.48) | CYP1A2CYP3A4HTTCYP2D6MAPT | |
| Sulfuric Acid SCHEMBL8070176 | 0.78 | POLB (0.50) | ALDH1A1CYP3A4HTTMAPTKDM4D | |
| SCHEMBL11481834 | 0.78 | RELA (0.43) | ALDH1A1MAPTLMNAMEN1KMT2A | |
| SCHEMBL11639159 | 0.78 | CYP3A4 (0.52) | CYP1A2ALDH1A1CYP3A4HTTCYP2D6 | |
| Sulfuric Acid SCHEMBL8645602 | 0.77 | POLB (0.49) | ALDH1A1CYP3A4HTTMAPTKDM4D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0359618-B1 | 2-SUBSTITUTED PARA-AMINOPHENOLS AND THEIR USE IN THE COLORATION OF KERATINIC FIBRES | L'OREAL (FR) | 1993-03-17 | — | — | EP | disclosed |
| EP-0359618-A1 | 2-Substituted para-aminophenols and their use in the coloration of keratinic fibres | L'OREAL (FR) | 1990-03-21 | — | — | EP | disclosed |