Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CASR | P41180 | 2/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.56 |
| ▸ | MEN1 | O00255 | 2/20 | 0.56 |
| ▸ | ADRB3 | P13945 | 5/20 | 0.55 |
| ▸ | ADRB2 | P07550 | 3/20 | 0.55 |
| ▸ | ADRB1 | P08588 | 3/20 | 0.55 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.53 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.53 |
| ▸ | GAA | P10253 | 1/20 | 0.52 |
| ▸ | MAPT | P10636 | 1/20 | 0.52 |
| ▸ | ATM | Q13315 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.51 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.51 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6320450 | 1.00 | CASR (0.58) | CASRKMT2AMEN1ADRB3ADRB2 | |
| SCHEMBL6319503 | 0.80 | KMT2A (0.63) | CASRKMT2AMEN1ADRB3ADRB2 | |
| SCHEMBL6319499 | 0.80 | KMT2A (0.63) | CASRKMT2AMEN1ADRB3ADRB2 | |
| SCHEMBL11240101 | 0.79 | ADRB3 (0.64) | CASRKMT2AMEN1ADRB3ADRB2 | |
| SCHEMBL6320370 | 0.78 | KMT2A (0.64) | CASRKMT2AMEN1ADRB3ADRB2 | |
| SCHEMBL6321160 | 0.78 | KMT2A (0.64) | CASRKMT2AMEN1ADRB3ADRB2 | |
| SCHEMBL7028696 | 0.78 | ADRB1 (0.50) | KMT2AMEN1ADRB3ADRB2ADRB1 | |
| Hydrochloric Acid SCHEMBL6326505 | 0.76 | KMT2A (0.67) | CASRKMT2AMEN1ADRB3ADRB2 | |
| Hydrochloric Acid SCHEMBL7605228 | 0.76 | CYP2D6 (0.55) | KMT2AMEN1ADRB3ADRB2ADRB1 | |
| SCHEMBL20049935 | 0.76 | KMT2A (0.67) | CASRKMT2AMEN1ADRB3ADRB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050043371-A1 | Aminoalcohol derivatives and their use as beta 3 adrenergic agonists | FUJISAWA PHARMACEUTICAL CO. LTD. (JP) | 2005-02-24 | — | — | US | disclosed |
| US-20030181726-A1 | Aminoalcohol derivatives and their use as beta 3 adrenergic agonists | FUJISAWA PHARMACEUTICAL CO. LTD. (JP) | 2003-09-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050043371-A1 | Aminoalcohol derivatives and their use as beta 3 adrenergic agonists | ADRB1, ADRB3, ADRB2 | CASR 2658/4885KMT2A 3075/4885MEN1 3533/4885 |
| US-20030181726-A1 | Aminoalcohol derivatives and their use as beta 3 adrenergic agonists | ADRB1, ADRB3, ADRB2 | CASR 2834/4885KMT2A 3010/4885MEN1 3327/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.