Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | GLA | P06280 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | CRHBP | P24387 | 1/20 | 0.38 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | HCRTR1 | O43613 | 4/20 | 0.34 |
| ▸ | HCRTR2 | O43614 | 4/20 | 0.34 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.34 |
| ▸ | FYN | P06241 | 2/20 | 0.34 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.34 |
| ▸ | PTGDR | Q13258 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6326445 | 0.77 | HCRTR1 (0.35) | CRHBPCRHR2HCRTR1HCRTR2KCNH2 | |
| SCHEMBL4114573 | 0.74 | DYRK1A (0.39) | MEN1KMT2AHCRTR1HCRTR2SMN1; SMN2 | |
| SCHEMBL4115040 | 0.73 | RECQL (0.47) | POLBFYN | |
| SCHEMBL4122248 | 0.71 | PDE4D (0.45) | ALDH1A1KDM4EMEN1KMT2AHCRTR1 | |
| SCHEMBL4120391 | 0.71 | MEN1 (0.43) | POLBMEN1KMT2AHCRTR1HCRTR2 | |
| SCHEMBL13800105 | 0.70 | ACHE (0.42) | MEN1KMT2AHCRTR1HCRTR2 | |
| Ethylene SCHEMBL4120382 | 0.70 | PDE4D (0.43) | ALDH1A1KDM4EMEN1KMT2AHCRTR1 | |
| Hydrochloric Acid SCHEMBL6167681 | 0.69 | POLB (0.53) | ALDH1A1KDM4EPOLBMEN1KMT2A | |
| SCHEMBL6167070 | 0.68 | HCRTR1 (0.38) | ALDH1A1KDM4EKMT2AHCRTR1HCRTR2 | |
| SCHEMBL13800272 | 0.68 | PDE4D (0.47) | ALDH1A1KMT2AHCRTR1HCRTR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050176764-A1 | Medicine for treating cancer | KOWA CO., LTD (JP) | 2005-08-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050176764-A1 | Medicine for treating cancer | HDAC4, HDAC3, NR4A3 | ALDH1A1 1788/4885KDM4E 446/4885GLA 1891/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.