Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCRTR1 | O43613 | 6/20 | 0.35 |
| ▸ | HCRTR2 | O43614 | 6/20 | 0.35 |
| ▸ | CRHBP | P24387 | 1/20 | 0.32 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.32 |
| ▸ | USP2 | O75604 | 1/20 | 0.32 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.32 |
| ▸ | PARP1 | P09874 | 1/20 | 0.32 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.31 |
| ▸ | FGFR2 | P21802 | 1/20 | 0.31 |
| ▸ | FGFR3 | P22607 | 1/20 | 0.31 |
| ▸ | EHMT2 | Q96KQ7 | 1/20 | 0.31 |
| ▸ | EHMT1 | Q9H9B1 | 1/20 | 0.31 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.31 |
| ▸ | SUV39H2 | Q9H5I1 | 1/20 | 0.31 |
| ▸ | WNK1 | Q9H4A3 | 1/20 | 0.31 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6326440 | 0.77 | ALDH1A1 (0.38) | HCRTR1HCRTR2CRHBPCRHR2KCNH2 | |
| SCHEMBL13800109 | 0.76 | HRH3 (0.42) | HCRTR1HCRTR2WNK1HRH3 | |
| SCHEMBL4114573 | 0.75 | DYRK1A (0.39) | HCRTR1HCRTR2 | |
| Hydrochloric Acid SCHEMBL4116101 | 0.75 | HRH3 (0.41) | HCRTR1HCRTR2HRH3 | |
| SCHEMBL4115040 | 0.74 | RECQL (0.47) | — | |
| SCHEMBL4122248 | 0.72 | PDE4D (0.45) | HCRTR1HCRTR2PARP1WNK1HRH3 | |
| SCHEMBL13800105 | 0.71 | ACHE (0.42) | HCRTR1HCRTR2WNK1 | |
| SCHEMBL13800275 | 0.70 | HCRTR1 (0.44) | HCRTR1HCRTR2 | |
| Ethylene SCHEMBL4120382 | 0.70 | PDE4D (0.43) | HCRTR1HCRTR2PARP1WNK1HRH3 | |
| Hydrochloric Acid SCHEMBL6167681 | 0.70 | POLB (0.53) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050176764-A1 | Medicine for treating cancer | KOWA CO., LTD (JP) | 2005-08-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050176764-A1 | Medicine for treating cancer | HDAC4, HDAC3, NR4A3 | HCRTR1 235/4885HCRTR2 342/4885CRHBP 1949/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.