Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | FAAH | O00519 | 8/20 | 0.33 |
| ▸ | CES2 | O00748 | 3/20 | 0.33 |
| ▸ | CES1 | P23141 | 6/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | MGAM | O43451 | 1/20 | 0.30 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
| ▸ | SI | P14410 | 1/20 | 0.30 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6320620 | 0.92 | LMNA (0.34) | LMNAFAAHCES2CES1MEN1 | |
| SCHEMBL9598364 | 0.82 | LMNA (0.50) | LMNAFAAHMGAMGAASI | |
| SCHEMBL196660 | 0.79 | LMNA (0.39) | LMNAFAAHCES2CES1MEN1 | |
| SCHEMBL20680197 | 0.78 | FAAH (0.36) | FAAHCES2CES1MEN1CYP1A2 | |
| SCHEMBL10570400 | 0.77 | MGAM (0.44) | LMNAFAAHHSD17B10MGAMGAA | |
| SCHEMBL10779438 | 0.77 | LMNA (0.44) | LMNAFAAHMGAMGAASI | |
| SCHEMBL106759 | 0.74 | LMNA (0.50) | LMNAMEN1KMT2AMGAMGAA | |
| SCHEMBL2306711 | 0.74 | LMNA (0.50) | LMNACYP1A2MGAMGAASI | |
| SCHEMBL6322467 | 0.74 | LMNA (0.37) | LMNA | |
| SCHEMBL6322477 | 0.74 | LMNA (0.37) | LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6893861-B1 | Method for producing trifluoro-3(r)-hydroxybutyric acid derivatives | LONZA AG (CH) | 2005-05-17 | — | — | US | disclosed |