Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DNMT3B | Q9UBC3 | 1/20 | 0.52 |
| ▸ | TSHR | P16473 | 6/20 | 0.43 |
| ▸ | HPGD | P15428 | 5/20 | 0.43 |
| ▸ | HTT | P42858 | 3/20 | 0.43 |
| ▸ | LMNA | P02545 | 4/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | NPC1 | O15118 | 2/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | ATM | Q13315 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | CNR2 | P34972 | 3/20 | 0.42 |
| ▸ | CNR1 | P21554 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6324626 | 0.93 | DNMT3B (0.57) | DNMT3BTSHRHPGDHTTLMNA | |
| SCHEMBL6334966 | 0.90 | MAPT (0.53) | DNMT3BTSHRHPGDHTTLMNA | |
| SCHEMBL6325218 | 0.78 | MAPT (0.53) | DNMT3BTSHRHPGDHTTLMNA | |
| SCHEMBL6323049 | 0.77 | HPGD (0.56) | DNMT3BTSHRHPGDHTTLMNA | |
| SCHEMBL6326044 | 0.75 | MAPT (0.56) | TSHRHPGDHTTLMNANPSR1 | |
| SCHEMBL6323935 | 0.73 | MAPT (0.52) | DNMT3BTSHRHPGDHTTLMNA | |
| SCHEMBL6334127 | 0.71 | CYP1A2 (0.52) | TSHRHPGDHTTLMNAMAPK1 | |
| SCHEMBL6326111 | 0.70 | TSHR (0.51) | TSHRHPGDHTTLMNAMAPK1 | |
| SCHEMBL6326412 | 0.70 | TSHR (0.51) | TSHRHPGDHTTLMNAMAPK1 | |
| SCHEMBL6333059 | 0.70 | SMN1; SMN2 (0.47) | TSHRHPGDLMNAALDH1A1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6924284-B2 | PARP inhibitors | ICOS CORPORATION (US) | 2005-08-02 | — | — | US | disclosed |