Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.50 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.46 |
| ▸ | MEP1B | Q16820 | 8/20 | 0.44 |
| ▸ | MEP1A | Q16819 | 1/20 | 0.43 |
| ▸ | BCHE | P06276 | 4/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.42 |
| ▸ | DRD2 | P14416 | 1/20 | 0.42 |
| ▸ | DRD1 | P21728 | 1/20 | 0.42 |
| ▸ | DRD4 | P21917 | 1/20 | 0.42 |
| ▸ | DRD5 | P21918 | 1/20 | 0.42 |
| ▸ | DRD3 | P35462 | 1/20 | 0.42 |
| ▸ | PPARG | P37231 | 1/20 | 0.41 |
| ▸ | RORC | P51449 | 1/20 | 0.41 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1456846 | 0.84 | MEP1B (0.60) | TSHRHSD17B10PTPN1MEP1BMEP1A | |
| SCHEMBL6651857 | 0.82 | TSHR (0.61) | TSHRHSD17B10MEP1BMEP1ACYP1A2 | |
| Hydrochloric Acid SCHEMBL9837391 | 0.82 | TSHR (0.47) | TSHRHSD17B10PTPN1MEP1BMEP1A | |
| SCHEMBL27379923 | 0.81 | KMT2A (0.46) | TSHRPTPN1MEP1BMEP1APPARG | |
| SCHEMBL1638524 | 0.81 | LOXL2 (0.59) | TSHRHSD17B10MEP1BMEP1A | |
| SCHEMBL6322584 | 0.79 | TSHR (0.48) | TSHRHSD17B10PTPN1MEP1BMEP1A | |
| SCHEMBL3350068 | 0.79 | CYP4F2 (0.59) | TSHRHSD17B10MEP1BCYP1A2CYP2D6 | |
| SCHEMBL3895302 | 0.79 | CYP4F2 (0.50) | PPARG | |
| SCHEMBL924897 | 0.79 | CYP4F2 (0.49) | — | |
| SCHEMBL611239 | 0.78 | TSHR (0.49) | TSHRHSD17B10PTPN1MEP1BMEP1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6855711-B1 | Pharmaceutical compositions comprising iron chelators for the treatment of neurodegenerative disorders and some novel iron chelators | YEDA RESEARCH AND DEVELOPMENT CO. LTD. (IL) | 2005-02-15 | — | — | US | claimed |
| US-6855711-B1 | Pharmaceutical compositions comprising iron chelators for the treatment of neurodegenerative disorders and some novel iron chelators | YEDA RESEARCH AND DEVELOPMENT CO. LTD. (IL) | 2005-02-15 | — | — | US | disclosed |