Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.59 |
| ▸ | CYP4F2 | P78329 | 2/20 | 0.57 |
| ▸ | CYP4A11 | Q02928 | 2/20 | 0.57 |
| ▸ | MEP1B | Q16820 | 6/20 | 0.55 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | RAB9A | P51151 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.49 |
| ▸ | MRGPRX4 | Q96LA9 | 2/20 | 0.48 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.46 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | MEP1A | Q16819 | 2/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3350068 | 0.95 | CYP4F2 (0.59) | LOXL2CYP4F2CYP4A11MEP1BSLC7A5 | |
| SCHEMBL10106423 | 0.89 | LOXL2 (0.64) | LOXL2CYP4F2CYP4A11MEP1BSLC7A5 | |
| SCHEMBL22145186 | 0.86 | LOXL2 (0.54) | LOXL2CYP4F2CYP4A11MEP1BSLC7A5 | |
| SCHEMBL16706893 | 0.85 | LOXL2 (0.62) | LOXL2CYP4F2CYP4A11MEP1BSLC7A5 | |
| SCHEMBL1638440 | 0.84 | HDAC1 (0.52) | LOXL2CYP4F2CYP4A11MEP1BALDH1A1 | |
| SCHEMBL1638230 | 0.83 | LOXL2 (0.45) | LOXL2CYP4F2CYP4A11MEP1BSLC7A5 | |
| SCHEMBL1456846 | 0.83 | MEP1B (0.60) | MEP1BSMN1; SMN2TSHRHSD17B10MRGPRX4 | |
| SCHEMBL1638227 | 0.82 | LOXL2 (0.44) | LOXL2CYP4F2CYP4A11MEP1BSLC7A5 | |
| SCHEMBL165622 | 0.81 | LOXL2 (0.66) | LOXL2CYP4F2CYP4A11MEP1BSLC7A5 | |
| SCHEMBL1206463 | 0.81 | HRH3 (0.55) | LOXL2CYP4F2CYP4A11ALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1724263-B1 | BASIC AMINE COMPOUND AND USE THEREOF | KUREHA CORP (JP) | 2014-03-05 | — | — | EP | disclosed |
| US-20110172212-A1 | AMINE-BASED COMPOUND AND USE THEREOF | KUREHA CORPORATION (JP) | 2011-07-14 | — | — | US | disclosed |
| US-7932281-B2 | Amine-based compound and use thereof | KUREHA CORPORATION (JP) | 2011-04-26 | — | — | US | disclosed |
| US-20070208007-A1 | Amine-Based Compound and Use Thereof | KUREHA CORPORATION (JP) | 2007-09-06 | — | — | US | disclosed |
| EP-1724263-A1 | BASIC AMINE COMPOUND AND USE THEREOF | Kureha Corporation (JP) | 2006-11-22 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110172212-A1 | AMINE-BASED COMPOUND AND USE THEREOF | NR0B2, NR5A2, NR1D2 | LOXL2 4133/4885CYP4F2 209/4885CYP4A11 353/4885 |
| US-20070208007-A1 | Amine-Based Compound and Use Thereof | NR0B2, NR5A2, NR2E1 | LOXL2 3824/4885CYP4F2 324/4885CYP4A11 430/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.