SCHEMBL6328472

SCHEMBL6328472

CCc1cc(C(c2cc(CC)c(O)c(CC)c2)c2ccc(O)cc2O)cc(CC)c1O

nearest known ligand 0.52

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
TYR P14679 6/20 0.44
HSP90AB1 P08238 1/20 0.39
GABRA1 P14867 1/20 0.38
GABRB2 P47870 1/20 0.38
MEN1 O00255 1/20 0.37
TP53 P04637 1/20 0.37
CYP3A4 P08684 1/20 0.37
ALOX5 P09917 1/20 0.37
MAPT P10636 1/20 0.37
ALOX15 P16050 1/20 0.37
TSHR P16473 1/20 0.37
HTT P42858 1/20 0.37
KMT2A Q03164 1/20 0.37
TDP1 Q9NUW8 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14461952 0.78 GABRA1 (0.48) GABRA1GABRB2CYP3A4ALOX15
SCHEMBL757574 0.77 TYR (0.47) TYR
SCHEMBL29375037 0.77 TYR (0.47) TYR
SCHEMBL19806852 0.75 TYR (0.45) TYRMEN1MAPTALOX15TSHR
SCHEMBL3793824 0.74 TYR (0.50) TYRKMT2ATDP1
SCHEMBL19621088 0.73 ESR1 (0.42) GABRA1GABRB2MEN1CYP3A4MAPT
SCHEMBL28642768 0.73 TYR (0.52) TYR
SCHEMBL19806928 0.72 TYR (0.52) TYR
SCHEMBL8092835 0.72 GABRA1 (0.48) GABRA1GABRB2CYP3A4ALOX5TSHR
SCHEMBL17356551 0.70 PRKCE (0.43) GABRA1GABRB2MEN1CYP3A4ALOX5

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6869742-B2 Positive photoresist composition TOKYO OHKA KOGYO CO., LTD. (JP) 2005-03-22 US disclosed
US-20020182531-A1 Positive photoresist composition TOKYO OHKA KOGYO CO., LTD. 2002-12-05 US disclosed
US-20020061458-A1 Positive photoresist composition TOKYO OHKA KOGYO CO., LTD. 2002-05-23 US disclosed