Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCRTR1 | O43613 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 4/20 | 0.45 |
| ▸ | HPGD | P15428 | 3/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.43 |
| ▸ | MAPT | P10636 | 3/20 | 0.43 |
| ▸ | CNR2 | P34972 | 3/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 3/20 | 0.41 |
| ▸ | HTT | P42858 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 2/20 | 0.40 |
| ▸ | GRM5 | P41594 | 1/20 | 0.40 |
| ▸ | CLPP | Q16740 | 1/20 | 0.40 |
| ▸ | CNR1 | P21554 | 1/20 | 0.40 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6326044 | 0.77 | MAPT (0.56) | LMNAHPGDALDH1A1MAPTCNR2 | |
| SCHEMBL6334127 | 0.77 | CYP1A2 (0.52) | LMNAHPGDALDH1A1MAPTCNR2 | |
| SCHEMBL6326111 | 0.76 | TSHR (0.51) | LMNAHPGDALDH1A1MAPTCNR2 | |
| SCHEMBL6326412 | 0.76 | TSHR (0.51) | LMNAHPGDALDH1A1MAPTCNR2 | |
| SCHEMBL6333059 | 0.76 | SMN1; SMN2 (0.47) | LMNAHPGDALDH1A1MAPTCNR2 | |
| SCHEMBL5077241 | 0.74 | GAA (0.50) | LMNAHPGDALDH1A1MAPTCNR2 | |
| SCHEMBL6332518 | 0.74 | HDAC1 (0.51) | LMNAHPGDALDH1A1CNR2CYP1A2 | |
| SCHEMBL6325850 | 0.74 | HDAC1 (0.51) | LMNAHPGDALDH1A1CNR2CYP1A2 | |
| SCHEMBL6328508 | 0.73 | CNR2 (0.40) | LMNAHPGDALDH1A1MAPTCNR2 | |
| SCHEMBL6334365 | 0.73 | HDAC1 (0.48) | LMNAHPGDALDH1A1MAPTCNR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6924284-B2 | PARP inhibitors | ICOS CORPORATION (US) | 2005-08-02 | — | — | US | disclosed |