SCHEMBL6328626

SCHEMBL6328626

CCOCCOC(=O)CC(O)C(F)(F)F

nearest known ligand 0.46

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.46
TSHR P16473 1/20 0.46
THRB P10828 1/20 0.41
HSD17B10 Q99714 2/20 0.33
DGKA P23743 1/20 0.32
EPHX2 P34913 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6322471 1.00 ALDH1A1 (0.46) ALDH1A1TSHRTHRBHSD17B10DGKA
SCHEMBL6321420 0.98 ALDH1A1 (0.44) ALDH1A1TSHRTHRBHSD17B10DGKA
SCHEMBL6321416 0.98 ALDH1A1 (0.44) ALDH1A1TSHRTHRBHSD17B10DGKA
SCHEMBL9362556 0.84 NAAA (0.34) ALDH1A1TSHRDGKA
SCHEMBL1532632 0.83 GAA (0.44) ALDH1A1TSHRHSD17B10
SCHEMBL16190580 0.83 GAA (0.44) ALDH1A1TSHRHSD17B10
SCHEMBL195939 0.83 GAA (0.44) ALDH1A1TSHRHSD17B10
SCHEMBL9362541 0.81 NAAA (0.44) ALDH1A1TSHRDGKA
SCHEMBL7054687 0.79 NAAA (0.52) ALDH1A1TSHRDGKA
SCHEMBL9937598 0.78 ALDH1A1 (0.52) ALDH1A1TSHRTHRBHSD17B10DGKA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6893861-B1 Method for producing trifluoro-3(r)-hydroxybutyric acid derivatives LONZA AG (CH) 2005-05-17 US disclosed