Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CG | P48736 | 1/20 | 0.44 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.41 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.37 |
| ▸ | ADAMTS5 | Q9UNA0 | 1/20 | 0.37 |
| ▸ | HTR1A | P08908 | 1/20 | 0.37 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.37 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.37 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.37 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.37 |
| ▸ | LTA4H | P09960 | 1/20 | 0.36 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.36 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.36 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.36 |
| ▸ | BRD4 | O60885 | 1/20 | 0.36 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | MAOB | P27338 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL865843 | 1.00 | PIK3CG (0.44) | PIK3CGADORA3SIRT2ADAMTS5HTR1A | |
| SCHEMBL29634508 | 1.00 | PIK3CG (0.44) | PIK3CGADORA3SIRT2ADAMTS5HTR1A | |
| SCHEMBL866306 | 1.00 | PIK3CG (0.44) | PIK3CGADORA3SIRT2ADAMTS5HTR1A | |
| SCHEMBL30092323 | 0.88 | SLC6A4 (0.43) | PIK3CGHTR1ASLC6A2SLC6A4SLC6A3 | |
| SCHEMBL25666164 | 0.88 | SLC6A4 (0.43) | PIK3CGHTR1ASLC6A2SLC6A4SLC6A3 | |
| SCHEMBL25666254 | 0.85 | HTR1A (0.47) | PIK3CGADORA3HTR1ASLC6A2SLC6A4 | |
| SCHEMBL866075 | 0.82 | ADORA3 (0.45) | PIK3CGADORA3SIRT2ADAMTS5SRD5A2 | |
| SCHEMBL14355700 | 0.80 | MAPT (0.39) | MAPTKDM4EALDH1A1POLBCA9 | |
| SCHEMBL24689334 | 0.79 | ADORA3 (0.43) | PIK3CGADORA3SIRT2LTA4HPLA2G2A | |
| SCHEMBL24689336 | 0.79 | FEN1 (0.42) | PIK3CG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 129 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115521254-B | Indanterol derivative and preparation method and application thereof | 中国药科大学 | 2024-05-31 | — | — | CN | disclosed |
| CN-115521254-A | Indanterol derivative and preparation method and application thereof | 中国药科大学 | 2022-12-27 | — | — | CN | disclosed |
| CN-107531636-B | Process for preparing indacaterol or salt thereof | 正大天晴药业集团股份有限公司 | 2022-11-25 | — | — | CN | disclosed |
| WO-2022172292-A1 | A PROCESS FOR PREPARING ABEDITEROL AND INTERMEDIATES THEREOF | GBR LABORATORIES PRIVATE LIMITED (IN) | 2022-08-18 | — | — | WO | disclosed |
| CN-114591236-A | Improved preparation method of indacaterol | 四川海思科制药有限公司 | 2022-06-07 | — | — | CN | disclosed |
| CN-109721534-B | Indacaterol maleate intermediate and preparation method and application thereof | 四川海思科制药有限公司 | 2022-05-20 | — | — | CN | disclosed |
| EP-3735406-B1 | A PROCESS FOR PREPARATION OF 5-(2-(SUBSTITUTED-AMINO)-1-HYDROXYETHYL)-8-(SUBSTITUTED-OXY) QUINOLIN-2(1H)-ONE | DEVA HOLDING AS (TR) | 2022-05-11 | — | — | EP | disclosed |
| CN-110343068-B | 2-amino-2-quinolyl ethanol beta 2-receptor agonist and preparation method and application thereof | 沈阳药科大学 | 2022-02-11 | — | — | CN | disclosed |
| CN-111808021-B | Preparation method of indacaterol and salt thereof | 上海谷森医药有限公司 | 2021-08-31 | — | — | CN | disclosed |
| CN-108101841-B | Method for preparing indacaterol or salt thereof | 江苏恒瑞医药股份有限公司 | 2021-04-06 | — | — | CN | disclosed |
| EP-1341542-A2 | ORGANIC COMPOUNDS | Novartis AG (CH) | 2003-09-10 | — | — | EP | disclosed |
| WO-2002045703-A2 | MIXTURES OR ORGANIC COMPOUNDS FOR THE TREATMENTOF AIRWAY DISEASES | NOVARTIS AG (CH) | 2002-06-13 | — | — | WO | disclosed |
| EP-1183240-A1 | BETA2-ADRENOCEPTOR AGONISTS | Novartis AG (CH) | 2002-03-06 | — | — | EP | disclosed |
| WO-2000075114-A1 | BETA2-ADRENOCEPTOR AGONISTS | NOVARTIS AG (CH) | 2000-12-14 | — | — | WO | disclosed |
| US-5750701-A | Heterocyclic ethanolamine derivatives with β-adrenoreceptor agonistic activity | SMITHKLINE BEECHAM PLC (GB) | 1998-05-12 | — | — | US | disclosed |
| EP-0750617-A1 | NOVEL HETEROCYCLIC ETHANOLAMINE DERIVATIVES WITH BETA-ADRENORECEPTOR AGONISTIC ACTIVITY | SMITHKLINE BEECHAM PLC (GB) | 1997-01-02 | — | — | EP | disclosed |
| WO-1995025104-A1 | NOVEL HETEROCYCLIC ETHANOLAMINE DERIVATIVES WITH BETA-ADRENORECEPTOR AGONISTIC ACTIVITY | SMITHKLINE BEECHAM P.L.C. (GB) | 1995-09-21 | — | — | WO | disclosed |
| US-4894219-A | ADRENERGIC BLOCKING AGENTS, ANALYZING | UNIVERSITY OF FLORIDA (US) | 1990-01-16 | — | — | US | disclosed |
| US-4853381-A | Ethanolamine compounds | GLAXO GROUP LIMITED (GB) | 1989-08-01 | — | — | US | disclosed |
| EP-0223410-A2 | Ethanolamine Derivatives | GLAXO GROUP LIMITED (GB) | 1987-05-27 | — | — | EP | disclosed |