Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CG | P48736 | 1/20 | 0.44 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.41 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.37 |
| ▸ | ADAMTS5 | Q9UNA0 | 1/20 | 0.37 |
| ▸ | HTR1A | P08908 | 1/20 | 0.37 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.37 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.37 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.37 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.37 |
| ▸ | LTA4H | P09960 | 1/20 | 0.36 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.36 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.36 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.36 |
| ▸ | BRD4 | O60885 | 1/20 | 0.36 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | MAOB | P27338 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL632919 | 1.00 | PIK3CG (0.44) | PIK3CGADORA3SIRT2ADAMTS5HTR1A | |
| SCHEMBL865843 | 1.00 | PIK3CG (0.44) | PIK3CGADORA3SIRT2ADAMTS5HTR1A | |
| SCHEMBL29634508 | 1.00 | PIK3CG (0.44) | PIK3CGADORA3SIRT2ADAMTS5HTR1A | |
| SCHEMBL30092323 | 0.88 | SLC6A4 (0.43) | PIK3CGHTR1ASLC6A2SLC6A4SLC6A3 | |
| SCHEMBL25666164 | 0.88 | SLC6A4 (0.43) | PIK3CGHTR1ASLC6A2SLC6A4SLC6A3 | |
| SCHEMBL25666254 | 0.85 | HTR1A (0.47) | PIK3CGADORA3HTR1ASLC6A2SLC6A4 | |
| SCHEMBL866075 | 0.82 | ADORA3 (0.45) | PIK3CGADORA3SIRT2ADAMTS5SRD5A2 | |
| SCHEMBL14355700 | 0.80 | MAPT (0.39) | MAPTKDM4EALDH1A1POLBCA9 | |
| SCHEMBL24689334 | 0.79 | ADORA3 (0.43) | PIK3CGADORA3SIRT2LTA4HPLA2G2A | |
| SCHEMBL24689336 | 0.79 | FEN1 (0.42) | PIK3CG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 102 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240208951-A1 | A PROCESS FOR PREPARING NAVAFENTEROL AND INTERMEDIATES THEREOF | GBR LABORATORIES PRIVATE LIMITED (IN) | 2024-06-27 | — | — | US | disclosed |
| US-20240208951-A1 | A PROCESS FOR PREPARING NAVAFENTEROL AND INTERMEDIATES THEREOF | GBR LABORATORIES PRIVATE LIMITED (IN) | 2024-06-27 | — | — | US | disclosed |
| US-20230322745-A1 | FUSED TRICYCLIC DERIVATIVE AND PHARMACEUTICAL APPLICATION THEREOF | CHIA TAI TIANQING PHARMACEUTICAL GROUP CO., LTD. (CN) | 2023-10-12 | — | — | US | disclosed |
| EP-4219485-A1 | FUSED TRICYCLIC DERIVATIVE AND PHARMACEUTICAL APPLICATION THEREOF | CHIA TAI TIANQING PHARMACEUTICAL GROUP CO., LTD. (CN) | 2023-08-02 | — | — | EP | disclosed |
| WO-2023077678-A1 | SMALL MOLECULE COMPOUND TARGETING SRSF6 PROTEIN AND PREPARATION METHOD THEREFOR AND USE THEREOF | 中国药科大学 | 2023-05-11 | — | — | WO | disclosed |
| WO-2023077678-A1 | SMALL MOLECULE COMPOUND TARGETING SRSF6 PROTEIN AND PREPARATION METHOD THEREFOR AND USE THEREOF | 中国药科大学 | 2023-05-11 | — | — | WO | disclosed |
| CN-115677577-A | Small molecular compound targeting SRSF6 protein, and preparation method and application thereof | 中国药科大学 | 2023-02-03 | — | — | CN | disclosed |
| WO-2022172292-A1 | A PROCESS FOR PREPARING ABEDITEROL AND INTERMEDIATES THEREOF | GBR LABORATORIES PRIVATE LIMITED (IN) | 2022-08-18 | — | — | WO | disclosed |
| CN-114591236-A | Improved preparation method of indacaterol | 四川海思科制药有限公司 | 2022-06-07 | — | — | CN | disclosed |
| CN-109721534-B | Indacaterol maleate intermediate and preparation method and application thereof | 四川海思科制药有限公司 | 2022-05-20 | — | — | CN | disclosed |
| WO-2004087142-A1 | QUINOLINE-2-ONE-DERIVATIVES FOR THE TREATMENT OF AIRWAYS DISEASES | NOVARTIS AG (CH) | 2004-10-14 | — | — | WO | disclosed |
| US-6800643-B2 | CORTICOSTEROID AND AN INDANYL-QUINOLINONE COMPOUND | NOVARTIS AG (CH) | 2004-10-05 | — | — | US | disclosed |
| WO-2004037773-A1 | PHENETHANOLAMINE DERIVATIVE FOR THE TREATMENT OF RESPIRATORY DISEASES | GLAXO GROUP LIMITED (GB) | 2004-05-06 | — | — | WO | disclosed |
| US-20040038951-A1 | Organic compounds | NOVARTIS AG (CH) | 2004-02-26 | — | — | US | disclosed |
| WO-2004016578-A2 | ARYLETHANOLAMINE BETA2-ADRENORECEPTOR AGONIST COMPOUNDS | GLAXO GROUP LIMITED (GB) | 2004-02-26 | — | — | WO | disclosed |
| EP-1341542-A2 | ORGANIC COMPOUNDS | Novartis AG (CH) | 2003-09-10 | — | — | EP | disclosed |
| WO-2002045703-A2 | MIXTURES OR ORGANIC COMPOUNDS FOR THE TREATMENTOF AIRWAY DISEASES | NOVARTIS AG (CH) | 2002-06-13 | — | — | WO | disclosed |
| US-5750701-A | Heterocyclic ethanolamine derivatives with β-adrenoreceptor agonistic activity | SMITHKLINE BEECHAM PLC (GB) | 1998-05-12 | — | — | US | disclosed |
| EP-0750617-A1 | NOVEL HETEROCYCLIC ETHANOLAMINE DERIVATIVES WITH BETA-ADRENORECEPTOR AGONISTIC ACTIVITY | SMITHKLINE BEECHAM PLC (GB) | 1997-01-02 | — | — | EP | disclosed |
| WO-1995025104-A1 | NOVEL HETEROCYCLIC ETHANOLAMINE DERIVATIVES WITH BETA-ADRENORECEPTOR AGONISTIC ACTIVITY | SMITHKLINE BEECHAM P.L.C. (GB) | 1995-09-21 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040038951-A1 | Organic compounds | CYP11B2, NR3C2, CYP11B1 | PIK3CG 4345/4885ADORA3 1485/4885SIRT2 4285/4885 |
| US-20240208951-A1 | A PROCESS FOR PREPARING NAVAFENTEROL AND INTERMEDIATES THEREOF | CYP4A11, CYP4F11, XDH | PIK3CG 3213/4885ADORA3 1755/4885SIRT2 2004/4885 |
| US-20230322745-A1 | FUSED TRICYCLIC DERIVATIVE AND PHARMACEUTICAL APPLICATION THEREOF | CYP3A43, ABCB1, ABCB11 | PIK3CG 2472/4885ADORA3 1321/4885SIRT2 1729/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.