Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH5A1 | P51649 | 1/20 | 0.56 |
| ▸ | ABAT | P80404 | 1/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.50 |
| ▸ | ESR1 | P03372 | 4/20 | 0.50 |
| ▸ | ESR2 | Q92731 | 4/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.50 |
| ▸ | MAPT | P10636 | 2/20 | 0.48 |
| ▸ | CISD1 | Q9NZ45 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | THRB | P10828 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | NQO2 | P16083 | 2/20 | 0.44 |
| ▸ | SLC16A3 | O15427 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | SLC16A1 | P53985 | 1/20 | 0.44 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | F3 | P13726 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6329475 | 1.00 | ALDH5A1 (0.56) | ALDH5A1ABATALDH1A1ESR1ESR2 | |
| SCHEMBL6332996 | 0.78 | CYP2A6 (0.54) | ALDH1A1MAPTMEN1KMT2AHPGD | |
| SCHEMBL6332998 | 0.78 | CYP2A6 (0.54) | ALDH1A1MAPTMEN1KMT2AHPGD | |
| SCHEMBL6333729 | 0.78 | HSD17B10 (0.54) | ALDH1A1CYP2C9PTGS2 | |
| SCHEMBL6333730 | 0.78 | HSD17B10 (0.54) | ALDH1A1CYP2C9PTGS2 | |
| SCHEMBL19458752 | 0.78 | ALDH5A1 (0.54) | ALDH5A1ABATALDH1A1ESR1ESR2 | |
| SCHEMBL6331873 | 0.77 | ALDH1A1 (0.60) | ALDH1A1ESR1MAPTCYP3A4CYP2D6 | |
| SCHEMBL6331875 | 0.77 | ALDH1A1 (0.60) | ALDH1A1ESR1MAPTCYP3A4CYP2D6 | |
| SCHEMBL10952638 | 0.75 | NQO2 (0.75) | ALDH5A1ABATALDH1A1ESR1ESR2 | |
| SCHEMBL6337917 | 0.73 | ALDH1A1 (0.59) | ALDH1A1KDM4EMAPTTHRBNQO2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6949682-B2 | Cinnamaldehyde derivatives inhibiting growth of tumor cell and regulating cell cycle, preparations and pharmaceutical compositions thereof | KOREA RESEARCH INSTITUTE OF BIOSCIENCE AND BIOTECHNOLOGY (KR) | 2005-09-27 | — | — | US | claimed |
| US-6949682-B2 | Cinnamaldehyde derivatives inhibiting growth of tumor cell and regulating cell cycle, preparations and pharmaceutical compositions thereof | KOREA RESEARCH INSTITUTE OF BIOSCIENCE AND BIOTECHNOLOGY (KR) | 2005-09-27 | — | — | US | disclosed |
| US-20040254196-A1 | Cinnamaldehyde derivatives inhibiting growth of tumor cell and regulating cell cycle, preparations and pharmaceutical compositions thereof | KOREA RESEARCH INSTITUTE OF BIOSCIENCE AND BIOTECHNOLOGY (KR) | 2004-12-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040254196-A1 | Cinnamaldehyde derivatives inhibiting growth of tumor cell and regulating cell cycle, preparations and pharmaceutical compositions thereof | CCNI, CDC25C, CDC25B | ALDH5A1 59/4885ABAT 1660/4885ALDH1A1 125/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.