Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2A6 | P11509 | 1/20 | 0.54 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | CA1 | P00915 | 1/20 | 0.40 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.39 |
| ▸ | FOS | P01100 | 1/20 | 0.38 |
| ▸ | JUN | P05412 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.38 |
| ▸ | ACHE | P22303 | 1/20 | 0.38 |
| ▸ | PKM | P14618 | 2/20 | 0.38 |
| ▸ | HTT | P42858 | 2/20 | 0.38 |
| ▸ | ATM | Q13315 | 2/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | NLRP1 | Q9C000 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6332998 | 1.00 | CYP2A6 (0.54) | CYP2A6PTGS2SMN1; SMN2NPC1RAB9A | |
| SCHEMBL2940976 | 0.79 | ALDH1A1 (0.65) | CYP2A6PTGS2SMN1; SMN2NPC1RAB9A | |
| SCHEMBL2815007 | 0.79 | ALDH1A1 (0.65) | CYP2A6PTGS2SMN1; SMN2NPC1RAB9A | |
| SCHEMBL6329475 | 0.78 | ALDH5A1 (0.56) | PTGS2MAPTALDH1A1HPGDMEN1 | |
| SCHEMBL6329472 | 0.78 | ALDH5A1 (0.56) | PTGS2MAPTALDH1A1HPGDMEN1 | |
| SCHEMBL28470407 | 0.77 | CYP2A6 (0.50) | CYP2A6PTGS2SMN1; SMN2NPC1RAB9A | |
| SCHEMBL30873529 | 0.77 | NQO2 (0.53) | CYP2A6PTGS2SMN1; SMN2NPC1RAB9A | |
| SCHEMBL28470411 | 0.77 | CYP2A6 (0.50) | CYP2A6PTGS2SMN1; SMN2NPC1RAB9A | |
| SCHEMBL6333730 | 0.76 | HSD17B10 (0.54) | CYP2A6PTGS2ALDH1A1AKR1C3HTT | |
| SCHEMBL6333729 | 0.76 | HSD17B10 (0.54) | CYP2A6PTGS2ALDH1A1AKR1C3HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6949682-B2 | Cinnamaldehyde derivatives inhibiting growth of tumor cell and regulating cell cycle, preparations and pharmaceutical compositions thereof | KOREA RESEARCH INSTITUTE OF BIOSCIENCE AND BIOTECHNOLOGY (KR) | 2005-09-27 | — | — | US | disclosed |
| US-20040254196-A1 | Cinnamaldehyde derivatives inhibiting growth of tumor cell and regulating cell cycle, preparations and pharmaceutical compositions thereof | KOREA RESEARCH INSTITUTE OF BIOSCIENCE AND BIOTECHNOLOGY (KR) | 2004-12-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040254196-A1 | Cinnamaldehyde derivatives inhibiting growth of tumor cell and regulating cell cycle, preparations and pharmaceutical compositions thereof | CCNI, CDC25C, CDC25B | CYP2A6 1500/4885PTGS2 263/4885SMN1; SMN2 4338/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.