Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2C19 | P33261 | 2/20 | 0.35 |
| ▸ | NR5A2 | O00482 | 1/20 | 0.34 |
| ▸ | NR5A1 | Q13285 | 1/20 | 0.34 |
| ▸ | PLG | P00747 | 2/20 | 0.33 |
| ▸ | KLK1 | P06870 | 2/20 | 0.33 |
| ▸ | KLK6 | Q92876 | 2/20 | 0.33 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.33 |
| ▸ | HSP90AB1 | P08238 | 2/20 | 0.33 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.33 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.32 |
| ▸ | DAPK3 | O43293 | 1/20 | 0.32 |
| ▸ | RET | P07949 | 1/20 | 0.32 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.32 |
| ▸ | PIM1 | P11309 | 1/20 | 0.32 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.32 |
| ▸ | KDR | P35968 | 1/20 | 0.32 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.32 |
| ▸ | RPS6KA3 | P51812 | 1/20 | 0.32 |
| ▸ | LIMK1 | P53667 | 1/20 | 0.32 |
| ▸ | TYRO3 | Q06418 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL888175 | 0.92 | CYP2C19 (0.40) | CYP2C19NR5A2NR5A1PLGKLK1 | |
| Hydrochloric Acid SCHEMBL10359086 | 0.90 | CYP2C19 (0.39) | CYP2C19NR5A2NR5A1PLGKLK1 | |
| Dimethylamine SCHEMBL11342588 | 0.88 | NR5A2 (0.39) | CYP2C19NR5A2NR5A1PLGKLK1 | |
| SCHEMBL888409 | 0.84 | CYP2C19 (0.46) | CYP2C19HSP90AA1CHEK1DAPK3RET | |
| Glycolic Acid SCHEMBL9813127 | 0.84 | PLG (0.35) | CYP2C19NR5A2NR5A1PLGKLK1 | |
| Bromide SCHEMBL11681378 | 0.83 | CYP2C19 (0.44) | CYP2C19HSP90AA1CHEK1DAPK3RET | |
| Hydrochloric Acid SCHEMBL4107889 | 0.83 | CYP2C19 (0.44) | CYP2C19PLGKLK1KLK6CHEK1 | |
| SCHEMBL11343552 | 0.81 | ALDH1A1 (0.42) | CYP2C19NR5A2NR5A1PLGKLK1 | |
| Sulfuric Acid SCHEMBL11682511 | 0.80 | CYP2C19 (0.40) | CYP2C19CHEK1DAPK3RETPDGFRB | |
| Phosphoric Acid SCHEMBL11680419 | 0.80 | CYP2C19 (0.40) | CYP2C19NR5A2NR5A1PLGKLK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050090553-A1 | Compositions and method for treatment of chronic inflammatory diseases | SECANT PHARMA, LLC | 2005-04-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050090553-A1 | Compositions and method for treatment of chronic inflammatory diseases | PCCA, HMGB1, PTGES | CYP2C19 611/4885NR5A2 4281/4885NR5A1 3245/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.