Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 5/20 | 0.71 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.71 |
| ▸ | MEN1 | O00255 | 3/20 | 0.71 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.71 |
| ▸ | ATM | Q13315 | 3/20 | 0.66 |
| ▸ | NPC1 | O15118 | 5/20 | 0.62 |
| ▸ | RAB9A | P51151 | 5/20 | 0.62 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.59 |
| ▸ | POLB | P06746 | 3/20 | 0.50 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.50 |
| ▸ | GAA | P10253 | 2/20 | 0.50 |
| ▸ | PTPN7 | P35236 | 1/20 | 0.50 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.50 |
| ▸ | GPR3 | P46089 | 1/20 | 0.50 |
| ▸ | HTT | P42858 | 2/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | GLA | P06280 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28179893 | 0.90 | NPC1 (0.71) | L3MBTL1KMT2AMEN1TLR9ATM | |
| SCHEMBL3875050 | 0.89 | GPR3 (0.64) | L3MBTL1KMT2AMEN1TLR9ATM | |
| SCHEMBL85776 | 0.83 | ATM (0.71) | L3MBTL1KMT2AMEN1TLR9ATM | |
| SCHEMBL29361718 | 0.83 | ATM (0.71) | L3MBTL1KMT2AMEN1TLR9ATM | |
| SCHEMBL29466066 | 0.83 | GPR3 (0.71) | L3MBTL1KMT2AMEN1TLR9ATM | |
| SCHEMBL53107 | 0.83 | GPR3 (0.71) | L3MBTL1KMT2AMEN1TLR9ATM | |
| SCHEMBL28278675 | 0.79 | ATM (0.66) | L3MBTL1KMT2AMEN1TLR9ATM | |
| SCHEMBL11374483 | 0.79 | ATM (0.66) | L3MBTL1KMT2AMEN1TLR9ATM | |
| SCHEMBL3872734 | 0.79 | GPR3 (0.44) | L3MBTL1KMT2AMEN1TLR9NPC1 | |
| SCHEMBL21312375 | 0.79 | GPR3 (0.71) | L3MBTL1KMT2AMEN1TLR9ATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050124664-A1 | Urea thiadiazole inhibitors of plasminogen activator inhibior-1 | BRISTOL-MYERS SQUIBB CO. | 2005-06-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050124664-A1 | Urea thiadiazole inhibitors of plasminogen activator inhibior-1 | SERPINE1, SERPINC1, SERPINB1 | L3MBTL1 2991/4885KMT2A 4128/4885MEN1 1004/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.