Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.41 |
| ▸ | AOC3 | Q16853 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | BRD4 | O60885 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | DRD2 | P14416 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | CASR | P41180 | 1/20 | 0.38 |
| ▸ | FLT3 | P36888 | 1/20 | 0.37 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8298140 | 0.82 | ALOX5 (0.49) | ALOX5KDM4EALDH1A1MAPTLOXL2 | |
| SCHEMBL26012345 | 0.82 | ALOX5 (0.49) | ALOX5KDM4EALDH1A1MAPTLOXL2 | |
| SCHEMBL13178686 | 0.80 | KDM4E (0.51) | ALOX5KDM4EALDH1A1MAPTLOXL2 | |
| SCHEMBL7814836 | 0.80 | ALOX5 (0.50) | ALOX5KDM4EALDH1A1MAPTLOXL2 | |
| SCHEMBL6328994 | 0.79 | ALOX5 (0.47) | ALOX5KDM4EALDH1A1MAPTLOXL2 | |
| SCHEMBL21686641 | 0.79 | ALOX5 (0.50) | ALOX5KDM4EALDH1A1MAPTLMNA | |
| SCHEMBL4985929 | 0.77 | ALOX5 (0.54) | ALOX5KDM4EALDH1A1MAPTLOXL2 | |
| SCHEMBL336690 | 0.77 | ALOX5 (0.54) | ALOX5KDM4EALDH1A1MAPTLOXL2 | |
| SCHEMBL30733359 | 0.77 | ALOX5 (0.54) | ALOX5KDM4EALDH1A1MAPTLOXL2 | |
| SCHEMBL7267170 | 0.77 | ALOX5 (0.48) | ALOX5KDM4EALDH1A1MAPTLOXL2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6872835-B2 | Process for preparation of fused pyrroles | JAPAN SCIENCE & TECHNOLOGY CORPORATION (JP) | 2005-03-29 | — | — | US | disclosed |
| EP-1302459-B1 | PROCESSES FOR PREPARATION OF FUSED PYRROLES | JAPAN SCIENCE & TECH AGENCY (JP) | 2004-10-27 | — | — | EP | disclosed |
| US-20040049054-A1 | Process for preparation of fused pyrroles | JAPAN SCIENCE AND TECHNOLOGY CORPORATION (JP) | 2004-03-11 | — | — | US | disclosed |
| EP-1302459-A1 | PROCESSES FOR PREPARATION OF FUSED PYRROLES | Japan Science and Technology Corporation (JP) | 2003-04-16 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040049054-A1 | Process for preparation of fused pyrroles | IDO1, IDO2, PAH | ALOX5 2549/4885KDM4E 360/4885ALDH1A1 1591/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.