Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | DRD2 | P14416 | 2/20 | 0.42 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.42 |
| ▸ | FLT3 | P36888 | 1/20 | 0.42 |
| ▸ | AOC3 | Q16853 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 3/20 | 0.41 |
| ▸ | DAO | P14920 | 2/20 | 0.41 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | BRD4 | O60885 | 1/20 | 0.41 |
| ▸ | DDO | Q99489 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 2/20 | 0.40 |
| ▸ | DRD3 | P35462 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29875124 | 1.00 | ALOX5 (0.48) | ALOX5KDM4EALDH1A1MAPTLMNA | |
| SCHEMBL28099621 | 0.85 | DRD2 (0.47) | ALOX5KDM4EALDH1A1MAPTLMNA | |
| SCHEMBL5249869 | 0.84 | ALOX5 (0.45) | ALOX5KDM4EALDH1A1MAPTLMNA | |
| SCHEMBL31612134 | 0.83 | ALOX5 (0.49) | ALOX5KDM4EALDH1A1MAPTLMNA | |
| SCHEMBL30863902 | 0.82 | DRD2 (0.45) | ALOX5KDM4EALDH1A1MAPTDRD2 | |
| SCHEMBL29170226 | 0.82 | LOXL2 (0.50) | ALOX5KDM4EALDH1A1MAPTLMNA | |
| SCHEMBL13178686 | 0.81 | KDM4E (0.51) | ALOX5KDM4EALDH1A1MAPTDRD2 | |
| SCHEMBL7814836 | 0.81 | ALOX5 (0.50) | ALOX5KDM4EALDH1A1MAPTDRD2 | |
| SCHEMBL26012345 | 0.80 | ALOX5 (0.49) | ALOX5KDM4EALDH1A1MAPTLMNA | |
| SCHEMBL8298140 | 0.80 | ALOX5 (0.49) | ALOX5KDM4EALDH1A1MAPTLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0439796-B1 | Indolylpropanols, process for their preparation, and their use and preparations containing them | BEIERSDORF LILLY GMBH (DE) | 1996-01-24 | — | — | EP | claimed |
| EP-0297380-B1 | Indolyl propanols, process for their preparation, their uses and preparation containing them | BEIERSDORF LILLY GMBH (DE) | 1994-10-05 | — | — | EP | claimed |
| US-5145849-A | Inotropic and antiarrythmia agents; sodium channel inhibitors | BEIERSDORF AKTIENGESELLSCHAFT (DE) | 1992-09-08 | — | — | US | claimed |
| US-4935414-A | New indolylpropanols, processes for their preparation and their use, and preparations containing the compounds | BEIERSDORF AG (DE) | 1990-06-19 | — | — | US | claimed |
| JP-4210979-A | — | — | None | — | — | JP | disclosed |
| EP-0439796-B1 | Indolylpropanols, process for their preparation, and their use and preparations containing them | BEIERSDORF LILLY GMBH (DE) | 1996-01-24 | — | — | EP | disclosed |
| EP-0297380-B1 | Indolyl propanols, process for their preparation, their uses and preparation containing them | BEIERSDORF LILLY GMBH (DE) | 1994-10-05 | — | — | EP | disclosed |
| US-5145849-A | Inotropic and antiarrythmia agents; sodium channel inhibitors | BEIERSDORF AKTIENGESELLSCHAFT (DE) | 1992-09-08 | — | — | US | disclosed |
| US-5145849-A | Inotropic and antiarrythmia agents; sodium channel inhibitors | BEIERSDORF AKTIENGESELLSCHAFT (DE) | 1992-09-08 | — | — | US | disclosed |
| JP-H04210979-A | INDOLYLPROPANOL, ITS PREPARATION AND USE AND FORMULATION CONTAINING IT | BEIERSDORF AG | 1992-08-03 | — | — | JP | disclosed |
| EP-0439796-A2 | Indolylpropanols, process for their preparation, and their use and preparations containing them | Beiersdorf-Lilly GmbH (DE) | 1991-08-07 | — | — | EP | disclosed |
| US-4935414-A | New indolylpropanols, processes for their preparation and their use, and preparations containing the compounds | BEIERSDORF AG (DE) | 1990-06-19 | — | — | US | disclosed |
| US-4935414-A | New indolylpropanols, processes for their preparation and their use, and preparations containing the compounds | BEIERSDORF AG (DE) | 1990-06-19 | — | — | US | disclosed |
| US-4935414-A | New indolylpropanols, processes for their preparation and their use, and preparations containing the compounds | BEIERSDORF AG (DE) | 1990-06-19 | — | — | US | disclosed |
| EP-0297380-A3 | INDOLYL PROPANOLS, PROCESS FOR THEIR PREPARATION, THEIR USES AND PREPARATION CONTAINING THEM | — | 1990-05-09 | — | — | EP | disclosed |
| EP-0297380-A2 | Indolyl propanols, process for their preparation, their uses and preparation containing them | Beiersdorf-Lilly GmbH (DE) | 1989-01-04 | — | — | EP | disclosed |