Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CPA1 | P15085 | 2/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.41 |
| ▸ | ALPI | P09923 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.41 |
| ▸ | XIAP | P98170 | 1/20 | 0.41 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.40 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.40 |
| ▸ | SLC15A1 | P46059 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.39 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.39 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.39 |
| ▸ | HTR2A | P28223 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27686290 | 1.00 | CPA1 (0.45) | CPA1HPGDCYP1A2PTPN1ALPI | |
| SCHEMBL5169748 | 0.83 | ALDH1A1 (0.46) | CPA1HPGDCYP1A2ALPIPKM | |
| SCHEMBL5170328 | 0.83 | ALDH1A1 (0.46) | CPA1HPGDCYP1A2ALPIPKM | |
| SCHEMBL5169742 | 0.83 | ALDH1A1 (0.46) | CPA1HPGDCYP1A2ALPIPKM | |
| SCHEMBL8202673 | 0.82 | CYP1A2 (0.53) | CPA1HPGDCYP1A2PTPN1ALPI | |
| SCHEMBL2319694 | 0.82 | CYP1A2 (0.53) | CPA1HPGDCYP1A2PTPN1ALPI | |
| Hydrochloric Acid SCHEMBL6336814 | 0.81 | CYP1A2 (0.52) | CPA1HPGDCYP1A2PTPN1ALPI | |
| SCHEMBL9709725 | 0.80 | HPGD (0.48) | HPGDALDH1A1MAPTSIGMAR1MEN1 | |
| SCHEMBL2059348 | 0.80 | MCL1 (0.43) | HPGDCYP1A2ALDH1A1MEN1KMT2A | |
| SCHEMBL13536371 | 0.80 | EPHX1 (0.47) | HPGDCYP1A2ALPIPKMPTGS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101037403-A | Method for synthesizing anti-aids drug amprenavir intermediate | UNIV XIAMEN (CN) | 2007-09-19 | — | — | CN | claimed |
| CN-101037403-A | Method for synthesizing anti-aids drug amprenavir intermediate | UNIV XIAMEN (CN) | 2007-09-19 | — | — | CN | disclosed |
| US-RE38796-E1 | Process for producing 3-amino-2-oxo-1-halogenopropane derivatives | AJINOMOTO CO.,INC. (JP) | 2005-09-13 | — | — | US | disclosed |
| EP-0774453-B1 | Process for producing 3-amino-2-oxo-1-halogenopropane derivatives | AJINOMOTO KK (JP) | 2002-02-06 | — | — | EP | disclosed |
| EP-1097919-A2 | Process for producing 4-amino-3-oxo-butanoic acid ester | Ajinomoto Co., Inc. (JP) | 2001-05-09 | — | — | EP | disclosed |
| US-5902887-A | Process for producing 3-amino-2-oxo-1-halogenopropane derivatives | AJINOMOTO CO., INC. (JP) | 1999-05-11 | — | — | US | disclosed |
| US-5767316-A | REACTING PROTECTED AMINO ACID WITH ALKALI METAL ENOLATE OF ACETATE, HALOGENATING, HYDROLYZING, DECARBOXYLATING | AJINOMOTO CO., INC. (JP) | 1998-06-16 | — | — | US | disclosed |
| EP-0774453-A1 | Process for producing 3-amino-2-oxo-1-halogenopropane derivatives | Ajinomoto Co., Inc. (JP) | 1997-05-21 | — | — | EP | disclosed |