Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 1/20 | 0.53 |
| ▸ | ALPI | P09923 | 1/20 | 0.50 |
| ▸ | PKM | P14618 | 1/20 | 0.50 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.50 |
| ▸ | XIAP | P98170 | 1/20 | 0.50 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.50 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
| ▸ | CPA1 | P15085 | 3/20 | 0.47 |
| ▸ | CPA3 | P15088 | 3/20 | 0.47 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.47 |
| ▸ | CPB1 | P15086 | 1/20 | 0.47 |
| ▸ | CPB2 | Q96IY4 | 1/20 | 0.47 |
| ▸ | SRR | Q9GZT4 | 2/20 | 0.46 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.46 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.46 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.46 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2319694 | 1.00 | CYP1A2 (0.53) | CYP1A2ALPIPKMPTGS1XIAP | |
| Hydrochloric Acid SCHEMBL6336814 | 0.98 | CYP1A2 (0.52) | CYP1A2ALPIPKMPTGS1XIAP | |
| SCHEMBL27799946 | 0.92 | SLC7A5 (0.49) | CYP1A2ALPIPKMPTGS1XIAP | |
| SCHEMBL25336940 | 0.90 | FPR2 (0.46) | CYP1A2ALPIPKMPTGS1XIAP | |
| SCHEMBL18039536 | 0.90 | MME (0.49) | CYP1A2 | |
| SCHEMBL25336942 | 0.90 | FPR2 (0.46) | CYP1A2ALPIPKMPTGS1XIAP | |
| SCHEMBL3800018 | 0.90 | MME (0.49) | CYP1A2 | |
| SCHEMBL1594754 | 0.86 | PPARG (0.53) | CPA1PTPN1 | |
| SCHEMBL31062607 | 0.86 | LDHA (0.58) | — | |
| SCHEMBL1594751 | 0.86 | PPARG (0.53) | CPA1PTPN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105152978-B | A kind of preparation method of the butanol of 3 tert-butoxycarbonylamino of (2R, 3S) 1 chlorine, 4 phenyl 2 | 上海应用技术学院 | 2017-08-25 | — | — | CN | claimed |
| EP-3737663-B1 | MANGANESE-CATALYSED HYDROGENATION OF ESTERS | UNIV COURT UNIV ST ANDREWS (GB) | 2023-02-22 | — | — | EP | disclosed |
| US-20210053932-A1 | MANGANESE-CATALYSED HYDROGENATION OF ESTERS | UNIVERSITY COURT OF THE UNIVERSITY OF ST ANDREWS (GB) | 2021-02-25 | — | — | US | disclosed |
| EP-3737663-A1 | MANGANESE-CATALYSED HYDROGENATION OF ESTERS | University Court of The University of St Andrews (GB) | 2020-11-18 | — | — | EP | disclosed |
| CN-105152978-B | A kind of preparation method of the butanol of 3 tert-butoxycarbonylamino of (2R, 3S) 1 chlorine, 4 phenyl 2 | 上海应用技术学院 | 2017-08-25 | — | — | CN | disclosed |
| CN-105175364-A | Method for preparing amprenavir midbody serving as anti-AIDS medicine | SHANGHAI INST TECHNOLOGY | 2015-12-23 | — | — | CN | disclosed |
| EP-0730570-B1 | METHOD FOR MAKING INTERMEDIATES USEFUL IN SYNTHESIS OF RETROVIRAL PROTEASE INHIBITORS | SEARLE & CO (US) | 2000-04-19 | — | — | EP | disclosed |
| US-5990341-A | Diastereoselective synthesis hydroxyethylene dipeptide isosteres | EMORY UNIVERSITY (US) | 1999-11-23 | — | — | US | disclosed |
| US-5587514-A | Diastereoselective synthesis of hydroxyethylene dipeptide isosteres | EMORY UNIVERSITY (US) | 1996-12-24 | — | — | US | disclosed |
| WO-1995014655-A1 | DIASTEREOSELECTIVE SYNTHESIS OF HYDROXYETHYLENE DIPEPTIDE ISOSTERES | EMORY UNIVERSITY (US) | 1995-06-01 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210053932-A1 | MANGANESE-CATALYSED HYDROGENATION OF ESTERS | ADH5, HDHD5, ADH1A | CYP1A2 337/4885ALPI 2393/4885PKM 1489/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.