Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | NPC1 | O15118 | 2/20 | 0.45 |
| ▸ | RAB9A | P51151 | 2/20 | 0.45 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.43 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.42 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.42 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.42 |
| ▸ | HTR2A | P28223 | 1/20 | 0.42 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.42 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.42 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.42 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.42 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.42 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | CTRB1 | P17538 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9709399 | 0.87 | MMP1 (0.50) | HPGDMEN1KMT2ANPC1RAB9A | |
| SCHEMBL14600180 | 0.82 | HPGD (0.48) | HPGDMEN1KMT2ANPC1RAB9A | |
| SCHEMBL9075534 | 0.81 | HPGD (0.47) | HPGDMEN1KMT2ANPC1RAB9A | |
| SCHEMBL9075532 | 0.81 | HPGD (0.47) | HPGDMEN1KMT2ANPC1RAB9A | |
| SCHEMBL9330375 | 0.80 | TP53 (0.48) | HPGDMEN1KMT2ANPC1RAB9A | |
| SCHEMBL5169748 | 0.80 | ALDH1A1 (0.46) | HPGDMEN1KMT2ANPC1RAB9A | |
| SCHEMBL5169742 | 0.80 | ALDH1A1 (0.46) | HPGDMEN1KMT2ANPC1RAB9A | |
| SCHEMBL27686290 | 0.80 | CPA1 (0.45) | HPGDMEN1KMT2ANPC1RAB9A | |
| SCHEMBL6330627 | 0.80 | CPA1 (0.45) | HPGDMEN1KMT2ANPC1RAB9A | |
| SCHEMBL5170328 | 0.80 | ALDH1A1 (0.46) | HPGDMEN1KMT2ANPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1992010510-A1 | DITHIOLANO- AND DITHIANOGLYCIN-CONTAINING RENIN-INHIBITING PEPTIDES, PROCESS FOR PRODUCING THE SAME AND THEIR USE IN MEDICAMENTS | BAYER AKTIENGESELLSCHAFT (DE) | 1992-06-25 | — | — | WO | disclosed |