Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | MAOA | P21397 | 2/20 | 0.42 |
| ▸ | MAOB | P27338 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | LTA4H | P09960 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.39 |
| ▸ | NISCH | Q9Y2I1 | 1/20 | 0.38 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.38 |
| ▸ | PTPRF | P10586 | 1/20 | 0.38 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.38 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.38 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8125173 | 0.76 | — | — | |
| SCHEMBL902817 | 0.76 | — | — | |
| SCHEMBL2650327 | 0.75 | MEN1 (0.50) | MAPTMAOAMEN1KMT2A | |
| SCHEMBL5816984 | 0.75 | MAPT (0.40) | ALDH1A1MAPTMAOAMAOBMEN1 | |
| SCHEMBL11868729 | 0.72 | KDM4E (0.31) | MAPTCYP3A4 | |
| SCHEMBL2090459 | 0.72 | GAA (0.34) | HTT | |
| SCHEMBL6566419 | 0.71 | ADH1B (0.50) | ALDH1A1MEN1KMT2ATAAR1 | |
| SCHEMBL5185913 | 0.71 | HRH1 (0.39) | ALDH1A1MEN1CYP1A2KMT2ALTA4H | |
| SCHEMBL8119643 | 0.71 | KDM4E (0.35) | ALDH1A1MAPTMEN1KMT2ALTA4H | |
| SCHEMBL15031 | 0.71 | CALM1 (0.32) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6951872-B2 | Monocyclic or bicyclic carbocycles and heterocycles as factor Xa inhibitors | BRISTOL-MYERS SQUIBB PHARMA COMPANY (US) | 2005-10-04 | — | — | US | disclosed |
| US-6710058-B2 | USE AS ANTICOAGULANT AGENTS FOR THERAPY AND PROPHYLAXIS OFTHROMBOEMBOLIC DISORDERS | BRISTOL-MYERS SQUIBB PHARMA COMPANY | 2004-03-23 | — | — | US | disclosed |
| EP-1337251-A1 | MONOCYCLIC OR BICYCLIC CARBOCYCLES AND HETEROCYCLES AS FACTOR XA INHIBITORS | Bristol-Myers Squibb Pharma Company (US) | 2003-08-27 | — | — | EP | disclosed |
| WO-2002102380-A1 | MONOCYCLIC OR BICYCLIC CARBOCYCLES AND HETEROCYCLES AS FACTOR XA INHIBITORS | BRISTOL-MYERS SQUIBB PHARMA COMPANY (US) | 2002-12-27 | — | — | WO | disclosed |
| EP-0520377-B1 | A process for the selective preparation of 4,4-methylene-bis-(N-phenylalkylcarbamate) | LUCKY LTD (KR) | 1998-02-25 | — | — | EP | disclosed |
| US-5384424-A | Methylating N-phenylalkylcarbamate using acid catalyst | LUCKY LIMITED (KR) | 1995-01-24 | — | — | US | disclosed |
| EP-0520377-A2 | A process for the selective preparation of 4,4-methylene-bis-(N-phenylalkylcarbamate) | LUCKY LTD. (KR) | 1992-12-30 | — | — | EP | disclosed |