Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADH1B | P00325 | 1/20 | 0.50 |
| ▸ | ADH1C | P00326 | 1/20 | 0.50 |
| ▸ | ADH1A | P07327 | 1/20 | 0.50 |
| ▸ | ADH7 | P40394 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8129473 | 0.78 | ALDH1A1 (0.41) | ADH1BADH1CADH1AADH7MEN1 | |
| SCHEMBL2090459 | 0.73 | GAA (0.34) | — | |
| SCHEMBL16935766 | 0.73 | KDM4E (0.37) | ALDH1A1 | |
| SCHEMBL5937200 | 0.72 | — | — | |
| SCHEMBL902817 | 0.72 | — | — | |
| SCHEMBL8125173 | 0.72 | — | — | |
| SCHEMBL2650327 | 0.72 | MEN1 (0.50) | ADH1BADH1CADH1AADH7MEN1 | |
| SCHEMBL6330694 | 0.71 | ALDH1A1 (0.43) | MEN1KMT2ATAAR1ALDH1A1 | |
| SCHEMBL7715270 | 0.71 | MAOA (0.36) | MEN1KMT2A | |
| SCHEMBL9654441 | 0.71 | MC4R (0.43) | MEN1KMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1377543-A1 | OXALIC ACID DERIVATIVES | MERCK PATENT GmbH (DE) | 2004-01-07 | — | — | EP | disclosed |
| WO-2002083630-A1 | OXALIC ACID DERIVATIVES | MERCK PATENT GMBH (DE) | 2002-10-24 | — | — | WO | disclosed |