Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LOXL2 | Q9Y4K0 | 2/20 | 0.58 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.50 |
| ▸ | CYP4F2 | P78329 | 2/20 | 0.49 |
| ▸ | CYP4A11 | Q02928 | 2/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.46 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.46 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.46 |
| ▸ | PNMT | P11086 | 1/20 | 0.46 |
| ▸ | CASR | P41180 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.45 |
| ▸ | PARP1 | P09874 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | BLM | P54132 | 1/20 | 0.44 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5662355 | 0.86 | LOXL2 (0.51) | LOXL2SLC7A5CYP4F2CYP4A11ALDH1A1 | |
| SCHEMBL9359858 | 0.86 | CYP4F2 (0.54) | LOXL2SLC7A5CYP4F2CYP4A11ALDH1A1 | |
| SCHEMBL4446181 | 0.84 | LOXL2 (0.62) | LOXL2SLC7A5CYP4F2CYP4A11ALDH1A1 | |
| SCHEMBL15671512 | 0.84 | LOXL2 (0.58) | LOXL2SLC7A5CYP4F2CYP4A11ALDH1A1 | |
| SCHEMBL3182845 | 0.83 | CYP4F2 (0.55) | LOXL2SLC7A5CYP4F2CYP4A11ADRB2 | |
| SCHEMBL22076564 | 0.83 | F2 (0.51) | LOXL2SLC7A5CYP4F2CYP4A11ADRB2 | |
| SCHEMBL23746337 | 0.82 | LOXL2 (0.48) | LOXL2SLC7A5CYP4F2CYP4A11ALDH1A1 | |
| SCHEMBL23732388 | 0.82 | LOXL2 (0.48) | LOXL2SLC7A5CYP4F2CYP4A11ALDH1A1 | |
| SCHEMBL23746338 | 0.82 | LOXL2 (0.48) | LOXL2SLC7A5CYP4F2CYP4A11ALDH1A1 | |
| SCHEMBL31226811 | 0.82 | LOXL2 (0.48) | LOXL2SLC7A5CYP4F2CYP4A11ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116829532-A | Substituted cyclohexane carboxamides, their preparation and their therapeutic use | 赛诺菲 | 2023-09-29 | — | — | CN | disclosed |
| US-6878734-B2 | Gastrin and cholecystokinin receptor ligands(II) | JAMES BLACK FOUNDATION LIMITED (GB) | 2005-04-12 | — | — | US | disclosed |
| US-20030199565-A1 | Gastrin and cholecystokinin receptor ligands(II) | JAMES BLACK FOUNDATION LIMITED (GB) | 2003-10-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030199565-A1 | Gastrin and cholecystokinin receptor ligands(II) | GRPR, CCKBR, GIPR | LOXL2 3530/4885SLC7A5 1259/4885CYP4F2 971/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.