Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIM2 | Q9P1W9 | 1/20 | 0.31 |
| ▸ | ACSS2 | Q9NR19 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2482302 | 0.65 | FFAR4 (0.35) | PIM2 | |
| SCHEMBL6241838 | 0.64 | NOTUM (0.31) | — | |
| SCHEMBL5734923 | 0.62 | SLC6A4 (0.37) | — | |
| SCHEMBL893223 | 0.61 | OPRM1 (0.53) | — | |
| SCHEMBL31748627 | 0.59 | CA1 (0.44) | — | |
| SCHEMBL11962271 | 0.59 | OPRM1 (0.55) | — | |
| SCHEMBL18802838 | 0.59 | ESR1 (0.38) | ACSS2 | |
| SCHEMBL18802831 | 0.58 | HRH3 (0.41) | — | |
| SCHEMBL10639780 | 0.58 | ALDH1A1 (0.61) | — | |
| SCHEMBL23017577 | 0.58 | OPRM1 (0.49) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2419419-B1 | 4-AZETIDINYL-1-PHENYL-CYCLOHEXANE ANTAGONISTS OF CCR2 | JANSSEN PHARMACEUTICA NV (BE) | 2014-12-03 | — | — | EP | disclosed |
| EP-2419419-A1 | 4-AZETIDINYL-1-PHENYL-CYCLOHEXANE ANTAGONISTS OF CCR2 | Janssen Pharmaceutica, N.V. (BE) | 2012-02-22 | — | — | EP | disclosed |
| WO-2010121046-A1 | 4-AZETIDINYL-1-PHENYL-CYCLOHEXANE ANTAGONISTS OF CCR2 | JANSSEN PHARMACEUTICA NV (BE) | 2010-10-21 | — | — | WO | disclosed |