Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTA4H | P09960 | 1/20 | 0.52 |
| ▸ | ACACB | O00763 | 2/20 | 0.50 |
| ▸ | PLK1 | P53350 | 1/20 | 0.50 |
| ▸ | CA12 | O43570 | 1/20 | 0.48 |
| ▸ | CA1 | P00915 | 1/20 | 0.48 |
| ▸ | CA2 | P00918 | 1/20 | 0.48 |
| ▸ | CA7 | P43166 | 1/20 | 0.48 |
| ▸ | CA9 | Q16790 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | MAOB | P27338 | 3/20 | 0.46 |
| ▸ | HRH3 | Q9Y5N1 | 3/20 | 0.46 |
| ▸ | PSMB1 | P20618 | 2/20 | 0.46 |
| ▸ | PSMB5 | P28074 | 2/20 | 0.46 |
| ▸ | PSMB2 | P49721 | 2/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12716987 | 0.88 | PSMB1 (0.49) | LTA4HACACBPLK1ALDH1A1LMNA | |
| SCHEMBL271059 | 0.87 | KDM4E (0.56) | LTA4HACACBPLK1CA12CA1 | |
| SCHEMBL84118 | 0.87 | SMN1; SMN2 (0.58) | LTA4HACACBPLK1CA12CA1 | |
| 1,4-Dipropoxybenzene SCHEMBL122039 | 0.83 | LTA4H (0.67) | LTA4HPLK1CA12CA1CA2 | |
| SCHEMBL29337533 | 0.83 | CA12 (0.50) | LTA4HACACBPLK1CA12CA1 | |
| SCHEMBL13311537 | 0.82 | NQO1 (0.67) | LTA4HPLK1CA12CA1CA2 | |
| SCHEMBL1456663 | 0.82 | THRA (0.45) | KDM4EMEN1KMT2AMAOBHRH3 | |
| SCHEMBL15384650 | 0.82 | NQO1 (0.54) | LTA4HACACBPLK1CA12CA1 | |
| SCHEMBL20486803 | 0.81 | LTA4H (0.66) | LTA4HALDH1A1MEN1KMT2AL3MBTL1 | |
| SCHEMBL10695520 | 0.81 | LTA4H (0.55) | LTA4HACACBPLK1ALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6852795-B2 | Prepolymeric (meth)acrylates with polycyclic or aromatic segments | 3M ESPE AG (DE) | 2005-02-08 | — | — | US | disclosed |
| EP-1284979-B1 | PREPOLYMERIC (METH)ACRYLATES WITH POLYCYCLIC OR AROMATIC SEGMENTS | 3M ESPE AG (DE) | 2004-12-29 | — | — | EP | disclosed |
| US-20030166816-A1 | Prepolymeric (meth) acrylates with polycyclic or aromatic segments | 3M INNOVATIVE PROPERTIES COMPANY | 2003-09-04 | — | — | US | disclosed |
| US-6566413-B1 | For dental and dental engineering applications | 3M ESPE AG (DE) | 2003-05-20 | — | — | US | disclosed |
| EP-1139973-B1 | POLYMERISABLE MATERIALS WHICH ARE BASED ON HARDENABLE SILOXANE COMPOUNDS | 3M ESPE AG (DE) | 2003-04-23 | — | — | EP | disclosed |
| EP-1139973-A2 | POLYMERISABLE MATERIALS WHICH ARE BASED ON HARDENABLE SILOXANE COMPOUNDS | ESPE Dental AG (DE) | 2001-10-10 | — | — | EP | disclosed |
| WO-2000038619-A2 | POLYMERISABLE MATERIALS WHICH ARE BASED ON HARDENABLE SILOXANE COMPOUNDS | 3M ESPE AG (DE) | 2000-07-06 | — | — | WO | disclosed |