Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.51 |
| ▸ | OPRL1 | P41146 | 3/20 | 0.49 |
| ▸ | OPRM1 | P35372 | 7/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | CCR3 | P51677 | 4/20 | 0.45 |
| ▸ | KCNA3 | P22001 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 3/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | ADRA2A | P08913 | 3/20 | 0.43 |
| ▸ | DRD4 | P21917 | 3/20 | 0.43 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.43 |
| ▸ | OPRD1 | P41143 | 3/20 | 0.43 |
| ▸ | OPRK1 | P41145 | 3/20 | 0.43 |
| ▸ | HRH2 | P25021 | 2/20 | 0.43 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.43 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.43 |
| ▸ | SCN5A | Q14524 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | ADRB2 | P07550 | 2/20 | 0.43 |
| ▸ | HTR2B | P41595 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL571239 | 1.00 | SIGMAR1 (0.51) | SIGMAR1OPRL1OPRM1POLBCCR3 | |
| SCHEMBL571259 | 0.87 | OPRM1 (0.38) | SIGMAR1OPRL1OPRM1CCR3MEN1 | |
| SCHEMBL571260 | 0.87 | OPRM1 (0.38) | SIGMAR1OPRL1OPRM1CCR3MEN1 | |
| SCHEMBL18409373 | 0.77 | MEN1 (0.52) | SIGMAR1OPRL1OPRM1POLBCCR3 | |
| SCHEMBL7381627 | 0.71 | NPC1 (0.65) | SIGMAR1OPRL1POLBMEN1KMT2A | |
| SCHEMBL12702280 | 0.71 | MEN1 (0.76) | SIGMAR1OPRL1OPRM1POLBMEN1 | |
| SCHEMBL327106 | 0.71 | CYP2B6 (0.45) | SIGMAR1OPRM1KCNA3KMT2AKCNH2 | |
| Acetic Acid SCHEMBL614395 | 0.70 | SIGMAR1 (0.72) | SIGMAR1OPRL1POLBCCR3KCNA3 | |
| SCHEMBL8097585 | 0.70 | SIGMAR1 (0.82) | SIGMAR1OPRL1POLBCCR3KCNA3 | |
| SCHEMBL2629517 | 0.69 | OPRM1 (0.70) | SIGMAR1OPRL1OPRM1POLBOPRD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2419433-A1 | HEPATITIS C VIRUS INHIBITORS | Bristol-Myers Squibb Company (US) | 2012-02-22 | — | — | EP | disclosed |