Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 6/20 | 0.38 |
| ▸ | OPRD1 | P41143 | 3/20 | 0.38 |
| ▸ | MEN1 | O00255 | 4/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.36 |
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.36 |
| ▸ | ADRA2A | P08913 | 3/20 | 0.36 |
| ▸ | DRD4 | P21917 | 3/20 | 0.36 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.36 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.36 |
| ▸ | HRH2 | P25021 | 2/20 | 0.36 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.36 |
| ▸ | SCN5A | Q14524 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | ADRB2 | P07550 | 2/20 | 0.36 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.36 |
| ▸ | HTR2B | P41595 | 2/20 | 0.36 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | SCN1A | P35498 | 2/20 | 0.36 |
| ▸ | SCN2A | Q99250 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL571260 | 1.00 | OPRM1 (0.38) | OPRM1OPRD1MEN1KMT2ASIGMAR1 | |
| SCHEMBL633413 | 0.87 | SIGMAR1 (0.51) | OPRM1OPRD1MEN1KMT2ASIGMAR1 | |
| SCHEMBL571239 | 0.87 | SIGMAR1 (0.51) | OPRM1OPRD1MEN1KMT2ASIGMAR1 | |
| SCHEMBL18112743 | 0.71 | CYP2B6 (0.41) | OPRM1OPRD1SIGMAR1KCNH2LMNA | |
| SCHEMBL327106 | 0.71 | CYP2B6 (0.45) | OPRM1KMT2ASIGMAR1KCNH2LMNA | |
| SCHEMBL7126061 | 0.70 | CYP2B6 (0.45) | OPRM1MEN1KMT2ASIGMAR1KCNH2 | |
| SCHEMBL2128439 | 0.69 | CYP2B6 (0.50) | OPRM1KMT2ASIGMAR1KCNH2LMNA | |
| SCHEMBL2127685 | 0.69 | CYP2B6 (0.50) | OPRM1KMT2ASIGMAR1KCNH2LMNA | |
| SCHEMBL580033 | 0.68 | OPRM1 (0.39) | OPRM1OPRD1OPRK1CYP1A2CYP3A4 | |
| SCHEMBL305263 | 0.68 | OPRM1 (0.39) | OPRM1OPRD1OPRK1CYP1A2CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011082077-A1 | HEPATITIS C VIRUS INHIBITORS | BRISTOL-MYERS SQUIBB COMPANY (US) | 2011-07-07 | — | — | WO | disclosed |