Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 2/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14506135 | 0.76 | — | — | |
| SCHEMBL9810808 | 0.75 | TSHR (0.30) | TSHR | |
| SCHEMBL10723520 | 0.74 | TSHR (0.35) | TSHR | |
| SCHEMBL4816226 | 0.73 | LMNA (0.42) | SMN1; SMN2LMNAALDH1A1HSD17B10MEN1 | |
| SCHEMBL31344505 | 0.71 | TSHR (0.36) | TSHR | |
| SCHEMBL2030414 | 0.69 | DNM1 (0.31) | ALDH1A1MEN1KMT2ATSHR | |
| SCHEMBL9810768 | 0.69 | — | — | |
| SCHEMBL30956293 | 0.67 | LMNA (0.36) | SMN1; SMN2LMNAALDH1A1HSD17B10MEN1 | |
| SCHEMBL5565331 | 0.66 | — | — | |
| SCHEMBL7562867 | 0.65 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9670324-B2 | Poly(thioesters), their applications and derivatives | CHEVRON PHILLIPS CHEMICAL COMPANY LP (US) | 2017-06-06 | — | — | US | disclosed |
| US-20160130401-A1 | Poly(Thioesters), Their Applications and Derivatives | CHEVRON PHILLIPS CHEMICAL COMPANY LP | 2016-05-12 | — | — | US | disclosed |
| US-20130211114-A1 | Poly(Thioesters), Their Applications and Derivatives | POLYMERIGHT, INC. (US) | 2013-08-15 | — | — | US | disclosed |
| US-8378060-B2 | Poly(thioesters), their applications and derivatives | POLYMERIGHT, INC. (US) | 2013-02-19 | — | — | US | disclosed |
| US-20120238718-A1 | Poly(thioesters), Their Applications and Derivatives | POLYMERIGHT, INC. (US) | 2012-09-20 | — | — | US | disclosed |
| EP-1620490-B1 | POLY ((POLYTHIOALKYL)ESTERS), THEIR APPLICATIONS AND DERIVATIVES | POLYMERIGHT INC (US) | 2012-07-04 | — | — | EP | disclosed |
| EP-2420523-A1 | Poly((Polythioalkyl)Esters) | Polymeright Inc. (US) | 2012-02-22 | — | — | EP | disclosed |
| EP-1620490-A4 | POLY ((POLYTHIOALKYL)ESTERS), THEIR APPLICATIONS AND DERIVATIVES | POLYMERIGHT INC (US) | 2009-05-27 | — | — | EP | disclosed |
| US-7087708-B2 | Poly ((polythioalkyl)esters), their applications and derivatives | POLYMERIGHT, INC. (US) | 2006-08-08 | — | — | US | disclosed |
| EP-1620490-A2 | POLY ((POLYTHIOALKYL)ESTERS), THEIR APPLICATIONS AND DERIVATIVES | Polymeright Inc. (US) | 2006-02-01 | — | — | EP | disclosed |
| US-20050143557-A1 | Poly((polythioalkyl)esters), their applications and derivatives | CHEVRON PHILLIPS CHEMICAL COMPANY LP | 2005-06-30 | — | — | US | disclosed |
| US-20040230030-A1 | Poly((polythioalkyl)esters), their applications and derivatives | CHEVRON PHILLIPS CHEMICAL COMPANY LP | 2004-11-18 | — | — | US | disclosed |
| WO-2004094522-A2 | POLY ((POLYTHIOALKYL)ESTERS), THEIR APPLICATIONS AND DERIVATIVES | POLYMERIGHT, INC. (US) | 2004-11-04 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120238718-A1 | Poly(thioesters), Their Applications and Derivatives | OXGR1, OXER1, OPRM1 | SMN1; SMN2 1776/4885LMNA 3639/4885ALDH1A1 821/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.