Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADAM17 | P78536 | 1/20 | 0.66 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.65 |
| ▸ | CTNNB1 | P35222 | 5/20 | 0.64 |
| ▸ | WNT3A | P56704 | 5/20 | 0.64 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.61 |
| ▸ | PBRM1 | Q86U86 | 1/20 | 0.61 |
| ▸ | ATM | Q13315 | 1/20 | 0.61 |
| ▸ | LMNA | P02545 | 1/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.57 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.56 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.56 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.56 |
| ▸ | NPC1 | O15118 | 2/20 | 0.55 |
| ▸ | RAB9A | P51151 | 2/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.55 |
| ▸ | HTT | P42858 | 1/20 | 0.55 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.55 |
| ▸ | MEN1 | O00255 | 1/20 | 0.55 |
| ▸ | MAPT | P10636 | 1/20 | 0.55 |
| ▸ | AANAT | Q16613 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29722237 | 1.00 | ADAM17 (0.66) | ADAM17GPR84CTNNB1WNT3AALDH1A1 | |
| SCHEMBL4056357 | 0.84 | ADAM17 (0.68) | ADAM17GPR84CTNNB1WNT3AALDH1A1 | |
| SCHEMBL3717752 | 0.84 | ADAM17 (0.68) | ADAM17GPR84CTNNB1WNT3AALDH1A1 | |
| SCHEMBL32685253 | 0.84 | ADAM17 (0.68) | ADAM17GPR84CTNNB1WNT3AALDH1A1 | |
| SCHEMBL1903034 | 0.82 | ADAM17 (0.66) | ADAM17GPR84CTNNB1WNT3AALDH1A1 | |
| SCHEMBL30839501 | 0.82 | ADAM17 (0.66) | ADAM17GPR84CTNNB1WNT3AALDH1A1 | |
| SCHEMBL31295276 | 0.82 | ADAM17 (0.66) | ADAM17GPR84CTNNB1WNT3AALDH1A1 | |
| SCHEMBL7007977 | 0.82 | ADAM17 (0.66) | ADAM17GPR84CTNNB1WNT3AALDH1A1 | |
| SCHEMBL4859074 | 0.81 | CTNNB1 (0.67) | ADAM17GPR84CTNNB1WNT3AALDH1A1 | |
| SCHEMBL6518029 | 0.81 | ADAM17 (0.73) | ADAM17GPR84CTNNB1WNT3AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114380815-A | Phytoalexin derivative and preparation method and application thereof | 河北工业大学 | 2022-04-22 | — | — | CN | disclosed |
| CN-107810961-B | Application of Topsentin alkaloid in resisting plant viruses and germs | 南开大学 | 2021-04-02 | — | — | CN | disclosed |
| CN-107814790-B | Topsentin derivative, preparation method thereof and application thereof in resisting plant viruses and germs | 南开大学 | 2021-03-30 | — | — | CN | disclosed |
| US-20050049245-A1 | Heteroaryl-ethanolamine derivatives as antiviral agents | PHARMACIA & UPJOHN COMPANY | 2005-03-03 | — | — | US | disclosed |
| US-6841685-B2 | Methods for making bis-heterocyclic alkaloids | STATE OF OREGON ACTING BY AND THROUGH THE STATE BOARD OF HIGHER EDUCATION ON BEHALF OF OREGON STATE UNIVERSITY (US) | 2005-01-11 | — | — | US | disclosed |
| WO-2004106345-A2 | HETEROARYL-ETHANOLAMINE DERIVATIVES AS ANTIVIRAL AGENTS | PHARMACIA & UPJOHN COMPANY (US) | 2004-12-09 | — | — | WO | disclosed |
| US-20030232988-A1 | Methods for making bis-heterocyclic alkaloids | STATE OF OREGON ACTING BY AND THROUGH THE STATE BOARD OF HIGHER EDUCATION ON BEHALF OF OREGON STATE UNIVERSITY,THE | 2003-12-18 | — | — | US | disclosed |
| EP-1026170-B1 | Erythromycin derivatives, their preparation and use as medicaments | AVENTIS PHARMA SA (FR) | 2003-01-15 | — | — | EP | disclosed |
| WO-2001094310-A1 | METHODS FOR MAKING BIS-HETEROCYCLIC ALKALOIDS | THE STATE OF OREGON ACTING BY AND THROUGH THE STATE BOARD OF HIGHER EDUCATION ON BEHALF OF OREGON STATE UNIVERSITY (US) | 2001-12-13 | — | — | WO | disclosed |
| US-6313101-B1 | ANTIBIOTICS | AVENTIS PHARMA S.A. (FR) | 2001-11-06 | — | — | US | disclosed |
| EP-1026170-A1 | Erythromycin derivatives, their preparation and use as medicaments | HOECHST MARION ROUSSEL (FR) | 2000-08-09 | — | — | EP | disclosed |
| US-5492919-A | IRRITABLE BOWEL DISORDER | SMITHKLINE BEECHAM P.L.C. (GB) | 1996-02-20 | — | — | US | disclosed |
| EP-0596933-A1 | 5-HT4 RECEPTOR ANTAGONISTS | SMITHKLINE BEECHAM PLC (GB) | 1994-05-18 | — | — | EP | disclosed |
| WO-1993002677-A1 | 5-HT4 RECEPTOR ANTAGONISTS | SMITHKLINE BEECHAM PLC (GB) | 1993-02-18 | — | — | WO | disclosed |
| US-4650800-A | Substituted pyrimidin-2-ones, the salts thereof, pharmaceutical compositions containing them and a method therefor | GLAXO GROUP LIMITED | 1987-03-17 | — | — | US | disclosed |
| EP-0084941-B1 | AMIDE DERIVATIVES | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1987-03-11 | — | — | EP | disclosed |
| US-4528282-A | Amide derivatives | IMPERIAL CHEMICAL INDUSTRIES, PLC (GB) | 1985-07-09 | — | — | US | disclosed |
| EP-0044705-B1 | SUBSTITUTED PYRIMIDIN-2-ONES, THE SALTS THEREOF, PROCESSES FOR THEIR PREPARATION, PHARMACEUTICAL COMPOSITIONS CONTAINING THEM AND A METHOD THEREFOR | GLAXO GROUP LIMITED (GB) | 1984-11-14 | — | — | EP | disclosed |
| EP-0084941-A1 | Amide derivatives | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1983-08-03 | — | — | EP | disclosed |
| EP-0044705-A1 | Substituted pyrimidin-2-ones, the salts thereof, processes for their preparation, pharmaceutical compositions containing them and a method therefor | GLAXO GROUP LIMITED (GB) | 1982-01-27 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030232988-A1 | Methods for making bis-heterocyclic alkaloids | CIAPIN1, AAAS, MDN1 | ADAM17 1557/4885GPR84 3098/4885CTNNB1 2965/4885 |
| US-20050049245-A1 | Heteroaryl-ethanolamine derivatives as antiviral agents | RPL35, ZC3HAV1, RPL5 | ADAM17 4219/4885GPR84 925/4885CTNNB1 4726/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.