Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 2/20 | 0.39 |
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | LPAR2 | Q9HBW0 | 1/20 | 0.38 |
| ▸ | LPAR3 | Q9UBY5 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.37 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.37 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.37 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28485593 | 0.84 | CES2 (0.42) | CYP2C19TDP1ALDH1A1L3MBTL1NPC1 | |
| SCHEMBL7116430 | 0.80 | TDP1 (0.46) | TDP1ALDH1A1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL29819688 | 0.79 | CHRM1 (0.49) | TDP1ALDH1A1SMN1; SMN2LMNACHRM2 | |
| SCHEMBL28356627 | 0.77 | FAAH (0.37) | CYP2C19TDP1ALDH1A1L3MBTL1SMN1; SMN2 | |
| SCHEMBL6821332 | 0.77 | TDP1 (0.71) | TDP1ALDH1A1L3MBTL1NPC1RAB9A | |
| SCHEMBL4806447 | 0.77 | TDP1 (0.71) | TDP1ALDH1A1L3MBTL1NPC1RAB9A | |
| SCHEMBL31746274 | 0.77 | TDP1 (0.71) | TDP1ALDH1A1L3MBTL1NPC1RAB9A | |
| SCHEMBL2420020 | 0.76 | TSHR (0.54) | TDP1ALDH1A1L3MBTL1NPC1RAB9A | |
| SCHEMBL3165169 | 0.76 | ALPI (0.47) | LMNA | |
| SCHEMBL6334265 | 0.75 | NPC1 (0.44) | TDP1ALDH1A1NPC1RAB9ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6949292-B2 | of polymers or oligomers with controlled structure on arbitrary solid surfaces; \"living\"/controlled free radical reaction | BOETTCHER HENRIK | 2005-09-27 | — | — | US | disclosed |
| US-20040142171-A1 | of polymers or oligomers with controlled structure on arbitrary solid surfaces; \"living\"/controlled free radical reaction | BOTTCHER HENRIK (DE) | 2004-07-22 | — | — | US | disclosed |
| US-6653415-B1 | Atom transfer radical polymerization (ATRP) by reaction with initiator | BOETTCHER HENRIK (DE) | 2003-11-25 | — | — | US | disclosed |