Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 2/20 | 0.44 |
| ▸ | RAB9A | P51151 | 2/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | CHRM2 | P08172 | 3/20 | 0.39 |
| ▸ | CHRM4 | P08173 | 3/20 | 0.39 |
| ▸ | CHRM1 | P11229 | 3/20 | 0.39 |
| ▸ | CHRM3 | P20309 | 3/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28626193 | 0.86 | NPC1 (0.42) | NPC1RAB9ASMN1; SMN2LMNACHRM2 | |
| SCHEMBL28626716 | 0.84 | SMN1; SMN2 (0.41) | NPC1RAB9ASMN1; SMN2LMNACHRM2 | |
| SCHEMBL7116430 | 0.79 | TDP1 (0.46) | NPC1RAB9ASMN1; SMN2LMNACHRM2 | |
| SCHEMBL2420020 | 0.79 | TSHR (0.54) | NPC1RAB9ASMN1; SMN2LMNACHRM2 | |
| SCHEMBL29819688 | 0.78 | CHRM1 (0.49) | SMN1; SMN2LMNACHRM2CHRM4CHRM1 | |
| SCHEMBL6335019 | 0.75 | CYP2C19 (0.41) | NPC1RAB9ASMN1; SMN2LMNACHRM2 | |
| SCHEMBL2417587 | 0.75 | LMNA (0.55) | NPC1RAB9ASMN1; SMN2LMNACHRM2 | |
| SCHEMBL2420427 | 0.73 | TSHR (0.53) | SMN1; SMN2LMNACHRM2CHRM4CHRM1 | |
| SCHEMBL287308 | 0.73 | MMP8 (0.56) | NPC1SMN1; SMN2LMNACHRM2CHRM1 | |
| SCHEMBL30062331 | 0.73 | MMP8 (0.56) | NPC1SMN1; SMN2LMNACHRM2CHRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6949292-B2 | of polymers or oligomers with controlled structure on arbitrary solid surfaces; \"living\"/controlled free radical reaction | BOETTCHER HENRIK | 2005-09-27 | — | — | US | disclosed |
| US-20040142171-A1 | of polymers or oligomers with controlled structure on arbitrary solid surfaces; \"living\"/controlled free radical reaction | BOTTCHER HENRIK (DE) | 2004-07-22 | — | — | US | disclosed |
| US-6653415-B1 | Atom transfer radical polymerization (ATRP) by reaction with initiator | BOETTCHER HENRIK (DE) | 2003-11-25 | — | — | US | disclosed |