Cis-3-Hexenol

Cis-3-Hexenol

SCHEMBL6335239

CC(CO)CC(C)c1ccccc1.CCC=CCCO

nearest known ligand 0.68

Full drug profile on Sugi Atlas →

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
TRPA1 O75762 7/20 0.68
TAAR1 Q96RJ0 3/20 0.36
AOC3 Q16853 2/20 0.33
ALDH1A1 P00352 1/20 0.33
CYP3A4 P08684 1/20 0.33
ALOX15 P16050 1/20 0.33
CYP2C19 P33261 1/20 0.33
RIPK1 Q13546 2/20 0.33
LMNA P02545 1/20 0.33
EPHX2 P34913 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Cis-3-Hexenol SCHEMBL6335235 1.00 TRPA1 (0.68) TRPA1TAAR1AOC3ALDH1A1CYP3A4
SCHEMBL295543 0.82 TRPA1 (1.00) TRPA1TAAR1AOC3ALDH1A1RIPK1
Acetic Acid SCHEMBL10395902 0.76 TRPA1 (0.85) TRPA1TAAR1AOC3CYP3A4CYP2C19
Cis-3-Hexenol SCHEMBL28144390 0.73 ALDH1A1 (0.48) ALDH1A1CYP3A4ALOX15LMNA
SCHEMBL16702621 0.72 TRPA1 (1.00) TRPA1TAAR1AOC3ALDH1A1RIPK1
Phthalic Acid SCHEMBL10807323 0.72 TRPA1 (0.77) TRPA1TAAR1ALDH1A1ALOX15RIPK1
SCHEMBL8207850 0.71 TRPA1 (0.69) TRPA1ALDH1A1CYP3A4CYP2C19
SCHEMBL5853428 0.70 RIPK1 (0.44) TRPA1TAAR1AOC3ALDH1A1CYP3A4
SCHEMBL5853431 0.70 RIPK1 (0.44) TRPA1TAAR1AOC3ALDH1A1CYP3A4
SCHEMBL10644871 0.70 TAAR1 (0.48) TRPA1TAAR1AOC3RIPK1LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6861402-B1 Pro-fragrances THE PROCTER & GAMBLE COMPANY (US) 2005-03-01 US claimed