SCHEMBL633699

SCHEMBL633699

CC(CO[Si](C)(C)C(C)(C)C)CC(=O)O

nearest known ligand 0.39

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
PGD P52209 2/20 0.39
ITGB3 P05106 1/20 0.34
ITGA2B P08514 1/20 0.34
BHMT Q93088 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23037384 0.84
SCHEMBL16689224 0.84 PGD (0.34) PGD
SCHEMBL28699911 0.82 BHMT (0.36) PGDBHMT
SCHEMBL22462725 0.82 TSHR (0.31)
SCHEMBL6301409 0.81 SLC22A6 (0.43) PGD
SCHEMBL6301406 0.81 SLC22A6 (0.43) PGD
SCHEMBL5103219 0.80 PGD (0.30) PGD
SCHEMBL5103212 0.80 PGD (0.30) PGD
SCHEMBL8076557 0.80
SCHEMBL22289099 0.79 PGD (0.33) PGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-107746414-B Method for preparing key chiral fragment of rupestonic acid 新疆维吾尔自治区药物研究所 2020-01-10 CN claimed
CN-107746414-B Method for preparing key chiral fragment of rupestonic acid 新疆维吾尔自治区药物研究所 2020-01-10 CN disclosed
EP-2419433-A1 HEPATITIS C VIRUS INHIBITORS Bristol-Myers Squibb Company (US) 2012-02-22 EP disclosed
WO-2010120621-A1 HEPATITIS C VIRUS INHIBITORS BRISTOL-MYERS SQUIBB COMPANY (US) 2010-10-21 WO disclosed